The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers
I Cavallari, F Ciccarese, E Sharova, L Urso… - Cancers, 2021 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …
expression by blocking translation or inducing degradation of specific gene transcripts. The …
[HTML][HTML] Triple-negative breast cancer: current treatment strategies and factors of negative prognosis
A Baranova, M Krasnoselskyi, V Starikov… - Journal of medicine …, 2022 - ncbi.nlm.nih.gov
Breast cancer is the most common cancer in women and the most common cause of death
in working-age women. According to the results of immunohistochemical studies, 10–20% of …
in working-age women. According to the results of immunohistochemical studies, 10–20% of …
Non-coding RNAs as liquid biopsy biomarkers in cancer
Although non-coding RNAs have long been considered as non-functional “junk” RNAs,
accumulating evidence in the past decade indicates that they play a critical role in …
accumulating evidence in the past decade indicates that they play a critical role in …
Genetic heterogeneity, tumor microenvironment and immunotherapy in triple-negative breast cancer
E Kudelova, M Smolar, V Holubekova… - International Journal of …, 2022 - mdpi.com
Heterogeneity of triple-negative breast cancer is well known at clinical, histopathological,
and molecular levels. Genomic instability and greater mutation rates, which may result in the …
and molecular levels. Genomic instability and greater mutation rates, which may result in the …
MicroRNAs in extracellular vesicles: sorting mechanisms, diagnostic value, isolation, and detection technology
D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in Bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …
New molecular mechanisms and clinical impact of circRNAs in human cancer
G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …
implicated in cellular physiological functions but also in the evolution of various human …
Notch signaling in acute inflammation and sepsis
N Gallenstein, L Tichy, MA Weigand… - International Journal of …, 2023 - mdpi.com
Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and
homeostasis of immune cells. Besides, this pathway is also directly involved in the …
homeostasis of immune cells. Besides, this pathway is also directly involved in the …
Circular RNAs as potential biomarkers in breast cancer
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …
management of this disease depends on imaging together with immunohistochemical and …
Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies
The clinical management of bladder cancer (BC) has become an increasing challenge due
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …
Unraveling immune-related lncRNAs in breast cancer molecular subtypes
C Mathias, JCD Muzzi, BB Antunes, DF Gradia… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BRCA) is the most leading cause of cancer worldwide. It is a heterogeneous
disease with at least five molecular subtypes including luminal A, luminal B, basal-like …
disease with at least five molecular subtypes including luminal A, luminal B, basal-like …