The formation of blood clots—thrombosis—at sites of atherosclerotic plaque rupture is a
major clinical problem despite ongoing improvements in antithrombotic therapy. Progress in …

This article presents a perspective on the importance of the autopsy in medical practice and
science based on experiences of the authors as physician-scientists involved in autopsy …

“You need a heart before you can have an attack”, growls the gumshoe Eddie Valiant in the
1988 cartoon-noir Who Framed Roger Rabbit. Valiant has a point, and not just the obvious …

This review provides a perspective on knowledge of ischemic heart disease (IHD) obtained
from the contemporary era of research which began in the 1960s and has continued to the …

This article introduces the Second Special Issue of Cardiovascular Pathology (CVP), the
official journal of the Society for Cardiovascular Pathology (SCVP). This CVP Special Issue …

Background: Despite substantial progress in modern preventive and clinical cardiology,
acute myocardial infarction (AMI) remains a central acute cardiac event. The aim of this …

Cardiogenic shock (CS) is a hemodynamically complex and highly morbid syndrome
characterized by circulatory collapse and inadequate end-organ perfusion due to impaired …

The relationship between health and exercise involves risks as well as rewards. This article
focuses on heart disease and the marathon to show how doctors have negotiated that …

This article reviews the development of early ideas regarding the origins and pathogenesis
of shock. The early history of shock related primarily to traumatic shock. More recent history …

In this issue of Blood, Chan et al have described mechanisms by which L5, the most
electronegative of 5 recognized fractions of low density lipoprotein (LDL), activates both …