Editing melon eIF4E associates with virus resistance and male sterility

GS Pechar, L Donaire, B Gosalvez… - Plant Biotechnology …, 2022 - Wiley Online Library
The cap‐binding protein eIF4E, through its interaction with eIF4G, constitutes the core of the
eIF4F complex, which plays a key role in the circularization of mRNAs and their subsequent …

Characteristic hallmarks of aging and the impact on carcinogenesis

S Terracina, G Ferraguti, C Petrella… - Current Cancer Drug …, 2023 - ingentaconnect.com
Evidence shows that there is a synergistic, bidirectional association between cancer and
aging with many shared traits. Age itself is a risk factor for the onset of most cancers, while …

Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins

Q Yu, Z Wang, Y Tu, Y Cao, H Zhu, J Shao… - Bioorganic …, 2024 - Elsevier
Intrinsically disordered proteins (IDPs) are characterized by their inability to adopt well-
defined tertiary structures under physiological conditions. Nonetheless, they often play …

Uterine secretome: What do the proteins say about maternal-fetal communication in buffaloes?

VM Codognoto, FF de Souza, TR Cataldi… - Journal of …, 2024 - Elsevier
The aim was to compare the UF proteomics of pregnant and non-pregnant buffalo during
early pregnancy. Forty-four females were submitted to hormonal estrus synchronization and …

Antioxidant and Antiaging Properties of a Novel Synergistic Nutraceutical Complex: Readouts from an In Cellulo Study and an In Vivo Prospective, Randomized Trial

S Athanasopoulou, M Kapetanou, MG Magouritsas… - Antioxidants, 2022 - mdpi.com
Aging is a dynamic procedure that is developed in multiple layers and characterized by
distinct hallmarks. The use of biomarkers that target different hallmarks of aging is …