Context-specific regulation of extracellular vesicle biogenesis and cargo selection

AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

Z Fan, C Jiang, Y Wang, K Wang, J Marsh… - Nanoscale …, 2022 - pubs.rsc.org
Extracellular vesicles (EVs), as natural carriers of bioactive cargo, have a unique
micro/nanostructure, bioactive composition, and characteristic morphology, as well as …

Single extracellular vesicle analysis for early cancer detection

S Ferguson, KS Yang, R Weissleder - Trends in molecular medicine, 2022 - cell.com
Extracellular vesicles (EVs) are actively shed into the circulation from both cancer and host
cells. EVs are emerging as one of the diagnostic frontrunners for early cancer detection …

Theranostic signature of tumor-derived exosomes in cancer

S Kumar, R Dhar, LBSS Kumar, GG Shivji, R Jayaraj… - Medical Oncology, 2023 - Springer
Cancer is the most challenging global health crisis. In the recent times, studies on
extracellular vesicles (EVs) are adding a new chapter to cancer research and reports on EVs …

All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model

K Chattrairat, T Yasui, S Suzuki, A Natsume… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) have promising potential as biomarkers for early cancer
diagnosis. The EVs have been widely studied as biological cargo containing essential …

Engineering a tunable micropattern‐array assay to sort single extracellular vesicles and particles to detect RNA and protein in situ

J Zhang, XY Rima, X Wang… - Journal of …, 2023 - Wiley Online Library
The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of
physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of …

[HTML][HTML] Extracellular vesicles of probiotics: Shedding light on the biological activity and future applications

P Krzyżek, B Marinacci, I Vitale, R Grande - Pharmaceutics, 2023 - mdpi.com
For many decades, the proper functioning of the human body has become a leading
scientific topic. In the course of numerous experiments, a striking impact of probiotics on the …

Recent developments in biosensing methods for extracellular vesicle protein characterization

J Suthar, M Taub, RP Carney… - Wiley …, 2023 - Wiley Online Library
Research into extracellular vesicles (EVs) has grown significantly over the last few decades
with EVs being widely regarded as a source of biomarkers for human health and disease …

From conventional to microfluidic: progress in extracellular vesicle separation and individual characterization

M Chen, S Lin, C Zhou, D Cui, H Haick… - Advanced Healthcare …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are nanoscale membrane vesicles, which contain a wide variety
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …

Nanostructured‐Based Optical Readouts Interfaced with Machine Learning for Identification of Extracellular Vesicles

C del Real Mata, O Jeanne, M Jalali… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are shed from cancer cells into body fluids, enclosing molecular
information about the underlying disease with the potential for being the target cancer …