Biotechnological approaches in the production of plant secondary metabolites for treating human viral diseases: Prospects and challenges.
M Mahmoudieh, MR Naghavi, ZM Sobri… - Biocatalysis and …, 2024 - Elsevier
Over the last couple of decades, three highly pathogenic and deadly human coronaviruses
have posed dreadful impacts on human life, namely SARS-CoV, MERS-CoV and SARS …
have posed dreadful impacts on human life, namely SARS-CoV, MERS-CoV and SARS …
[HTML][HTML] Crosstalk between hypoxic cellular micro-environment and the immune system: a potential therapeutic target for infectious diseases
There are overwhelming reports on the promotional effect of hypoxia on the malignant
behavior of various forms of cancer cells. This has been proposed and tested exhaustively in …
behavior of various forms of cancer cells. This has been proposed and tested exhaustively in …
The natural compound Sanggenon C inhibits PRRSV infection by regulating the TRAF2/NF-κB signalling pathway
X Liu, Y Zhu, D Wang, R Feng, Z Chen, Z Zheng… - Veterinary …, 2023 - Springer
Porcine reproductive and respiratory syndrome (PRRS) is a serious infectious disease and
one of the major causes of death in the global pig industry. PRRS virus (PRRSV) strains …
one of the major causes of death in the global pig industry. PRRS virus (PRRSV) strains …
Daqing formula ameliorated allergic asthma and airway dysbacteriosis in mice challenged with ovalbumin and ampicillin
L Wu, QY Peng, XJ Li, MY Guo, JQ He, HZ Ying… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Asthma is a chronic airway inflammatory disease that can
lead to several complications caused by bacterial infections. However, recurrent attacks of …
lead to several complications caused by bacterial infections. However, recurrent attacks of …
Novel thiosemicarbazide-based β-carboline derivatives as α-glucosidase inhibitors: Synthesis and biological evaluation
B Liang, D Xiao, SH Wang, X Xuetao - European Journal of Medicinal …, 2024 - Elsevier
In the quest for potent α-glucosidase inhibitors to combat diabetes, a series of novel
thiosemicarbazide-based β-carboline derivatives (CTL1∼ 36) were synthesized and …
thiosemicarbazide-based β-carboline derivatives (CTL1∼ 36) were synthesized and …
Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections
J Yang#, L Xu#, Y Zhou, M Cui, D Liu, J Wang… - Microbial Cell …, 2024 - Springer
Background A novel plasmid-mediated resistance–nodulation–division (RND) efflux pump
gene cluster tmexCD1-toprJ1 in Klebsiella pneumoniae tremendously threatens the use of …
gene cluster tmexCD1-toprJ1 in Klebsiella pneumoniae tremendously threatens the use of …
In Vitro Effect of 9, 9′-Norharmane Dimer against Herpes Simplex Viruses
MM Gonzalez, MG Vizoso-Pinto… - International Journal of …, 2024 - mdpi.com
Herpes simplex virus (HSV) infections are highly widespread among humans, producing
symptoms ranging from ulcerative lesions to severe diseases such as blindness and life …
symptoms ranging from ulcerative lesions to severe diseases such as blindness and life …
Molecular networking-based mass spectral identification of Brucea javanica (L.) Merr. metabolites and their selective binding affinities for dengue virus enzymes
NSAM Yousof, A Afzan, M Zainol, SIA Bakar… - Fitoterapia, 2024 - Elsevier
Brucea javanica, a valued traditional medicinal plant in Malaysia, known for its fever-treating
properties yet remains underexplored for its potential antiviral properties against dengue …
properties yet remains underexplored for its potential antiviral properties against dengue …
[HTML][HTML] The β-carboline analogs as a potent inhibitor for Alzheimer's Disease, molecular docking and dynamics simulation study
The β-carboline scaffold are very potent for encouraging molecular interactions with a wide
range of Alzheimer's target. Based on biological importance of carboline nucleus, we have …
range of Alzheimer's target. Based on biological importance of carboline nucleus, we have …
Identification of potential antiviral compounds from Egyptian marine algae against influenza A virus
B M. Hassen, SH Rashedy, A Mostafa… - Natural Product …, 2023 - Taylor & Francis
Influenza is a contagious viral infection of the respiratory tract, affecting nearly 10% of the
world's population, each year. The aim of this study was to extract and identify antiviral …
world's population, each year. The aim of this study was to extract and identify antiviral …