Over the last couple of decades, three highly pathogenic and deadly human coronaviruses
have posed dreadful impacts on human life, namely SARS-CoV, MERS-CoV and SARS …

There are overwhelming reports on the promotional effect of hypoxia on the malignant
behavior of various forms of cancer cells. This has been proposed and tested exhaustively in …

Porcine reproductive and respiratory syndrome (PRRS) is a serious infectious disease and
one of the major causes of death in the global pig industry. PRRS virus (PRRSV) strains …

Ethnopharmacological relevance Asthma is a chronic airway inflammatory disease that can
lead to several complications caused by bacterial infections. However, recurrent attacks of …

In the quest for potent α-glucosidase inhibitors to combat diabetes, a series of novel
thiosemicarbazide-based β-carboline derivatives (CTL1∼ 36) were synthesized and …

Background A novel plasmid-mediated resistance–nodulation–division (RND) efflux pump
gene cluster tmexCD1-toprJ1 in Klebsiella pneumoniae tremendously threatens the use of …

Herpes simplex virus (HSV) infections are highly widespread among humans, producing
symptoms ranging from ulcerative lesions to severe diseases such as blindness and life …

Brucea javanica, a valued traditional medicinal plant in Malaysia, known for its fever-treating
properties yet remains underexplored for its potential antiviral properties against dengue …

The β-carboline scaffold are very potent for encouraging molecular interactions with a wide
range of Alzheimer's target. Based on biological importance of carboline nucleus, we have …

Influenza is a contagious viral infection of the respiratory tract, affecting nearly 10% of the
world's population, each year. The aim of this study was to extract and identify antiviral …