Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Brain-derived neurotrophic factor (BDNF) is the most abundant neurotrophin in the adult
brain and functions as both a primary neurotrophic signal and a neuromodulator. It serves …

Dendrimers have been comprehensively used for cargo delivery, nucleic acid delivery
(genes, miRNA/siRNAs), delivery of macromolecules, and other various biomedical …

Neurodegenerative diseases (NDs) continue to burden human lives and economic
conditions. They continue to challenge the healthcare system due to the associated …

In vivo imaging has enabled impressive advances in biological research, both preclinical
and clinical, and researchers have an arsenal of imaging methods available …

The application of nanotechnology in biological and medical fields have resulted in the
creation of new devices, supramolecular systems, structures, complexes, and composites …

Enabling challenging applications of nanomedicine and precision medicine in the treatment
of neurodegenerative disorders requires deeper investigations of nanocarrier-mediated …

The adsorption of biomolecules on nanoparticles' surface ultimately depends on the
intermolecular forces, which dictate the mutual interaction transforming their physical …

The use of nanoparticles (NPs) as a therapeutic delivery system has expanded markedly
over the past decade, particularly regarding applications targeting the skin. The delivery of …

Numerous recently developed therapies have highlighted the advantages of using proteins
as therapeutics. However, in many protein delivery systems, the complicated carrier designs …