Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …

Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Tumor-infiltrating myeloid cells (TIMs) are key regulators in tumor progression, but the
similarity and distinction of their fundamental properties across different tumors remain …

Microglia are the resident macrophages of the central nervous system (CNS) acting as the
first line of defense in the brain by phagocytosing harmful pathogens and cellular debris …

Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Abstract M2-polarized, pro-tumoral tumor-associated macrophages (TAMs) express the
interleukin-4 receptor (IL4R) at higher levels compared with M1-polarized, anti-tumoral …

Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic
lung disease and predisposes individuals to acute lung injury and pulmonary infection …

Fibrosis progression in the lung commonly results in impaired functional gas exchange,
respiratory failure, or even death. In addition to the aberrant activation and differentiation of …

Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …

We profiled adaptive immunity in COVID-19 patients with active infection or after recovery
and created a repository of currently> 14 million B and T cell receptor (BCR and TCR) …