Candidate biomarkers in psychiatric disorders: state of the field

A Abi‐Dargham, SJ Moeller, F Ali… - World …, 2023 - Wiley Online Library
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …

Altering the course of schizophrenia: progress and perspectives

MJ Millan, A Andrieux, G Bartzokis… - Nature reviews Drug …, 2016 - nature.com
Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

Auditory dysfunction in schizophrenia: integrating clinical and basic features

DC Javitt, RA Sweet - Nature Reviews Neuroscience, 2015 - nature.com
Schizophrenia is a complex neuropsychiatric disorder that is associated with persistent
psychosocial disability in affected individuals. Although studies of schizophrenia have …

A meta-analysis of mismatch negativity in schizophrenia: from clinical risk to disease specificity and progression

MA Erickson, A Ruffle, JM Gold - Biological psychiatry, 2016 - Elsevier
Background The observation that mismatch negativity (MMN) is consistently impaired in
schizophrenia has generated considerable interest in the use of this biomarker as an index …

Sensory processing dysfunction in the personal experience and neuronal machinery of schizophrenia

DC Javitt, R Freedman - American Journal of Psychiatry, 2015 - Am Psychiatric Assoc
Sensory processing deficits, first investigated by Kraepelin and Bleuler as possible
pathophysiological mechanisms in schizophrenia, are now being recharacterized in the …

Gone to pot–a review of the association between cannabis and psychosis

R Radhakrishnan, ST Wilkinson, DC D'Souza - Frontiers in psychiatry, 2014 - frontiersin.org
Cannabis is the most commonly used illicit drug worldwide, with~ 5 million daily users
worldwide. Emerging evidence supports a number of associations between cannabis and …

Early detection and preventive intervention in schizophrenia: from fantasy to reality

JA Lieberman, SA Small… - American Journal of …, 2019 - Am Psychiatric Assoc
Scientific progress in understanding human disease can be measured by the effectiveness
of its treatment. Antipsychotic drugs have been proven to alleviate acute psychotic symptoms …

Language as a biomarker for psychosis: a natural language processing approach

CM Corcoran, VA Mittal, CE Bearden, RE Gur… - Schizophrenia …, 2020 - Elsevier
Human ratings of conceptual disorganization, poverty of content, referential cohesion and
illogical thinking have been shown to predict psychosis onset in prospective clinical high risk …

EEG-based measures in at-risk mental state and early stages of schizophrenia: a systematic review

A Perrottelli, GM Giordano, F Brando, L Giuliani… - Frontiers in …, 2021 - frontiersin.org
Introduction: Electrophysiological (EEG) abnormalities in subjects with schizophrenia have
been largely reported. In the last decades, research has shifted to the identification of …

Mismatch negativity (MMN) as an index of cognitive dysfunction

R Näätänen, ES Sussman, D Salisbury, VL Shafer - Brain topography, 2014 - Springer
Cognition is often affected in a variety of neuropsychiatric, neurological, and
neurodevelopmental disorders. The neural discriminative response, reflected in mismatch …