Atrial fibrillation pathophysiology: implications for management
Y Iwasaki, K Nishida, T Kato, S Nattel - Circulation, 2011 - Am Heart Assoc
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an important
contributor to population morbidity and mortality. An arrhythmia that is particularly common …
contributor to population morbidity and mortality. An arrhythmia that is particularly common …
Recent advances in the molecular pathophysiology of atrial fibrillation
Atrial fibrillation (AF) is an extremely common cardiac rhythm disorder that causes
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …
substantial morbidity and contributes to mortality. The mechanisms underlying AF are …
Atrial fibrillation: current knowledge and future directions in epidemiology and genomics
Atrial fibrillation (AF) is of public health importance and profoundly increases morbidity,
mortality, and healthrelated expenditures. Morbidities include the increased risks of …
mortality, and healthrelated expenditures. Morbidities include the increased risks of …
Role of miR-21 in the pathogenesis of atrial fibrosis
Atrial fibrosis is important for the pathogenesis of atrial fibrillation (AF) but the underlying
signal transduction is incompletely understood. We therefore studied the role of microRNA …
signal transduction is incompletely understood. We therefore studied the role of microRNA …
Atrial cardiomyopathy: pathophysiology and clinical consequences
A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …
annual increase of 5 million cases. Most AF patients have an established form of an atrial …
The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and its prevalence is
increasing with the ageing of the population. Presently available treatment options are far …
increasing with the ageing of the population. Presently available treatment options are far …
[HTML][HTML] Extracellular/circulating microRNAs and their potential role in cardiovascular disease
H Zhu, GC Fan - American journal of cardiovascular disease, 2011 - ncbi.nlm.nih.gov
Abstract microRNAs (miRs, miRNAs) are small non-coding RNAs that regulate hundreds of
gene expression. Numerous studies have demonstrated that miRNAs are not only found …
gene expression. Numerous studies have demonstrated that miRNAs are not only found …
Role for MicroRNA-21 in atrial profibrillatory fibrotic remodeling associated with experimental postinfarction heart failure
S Cardin, E Guasch, X Luo, P Naud… - Circulation …, 2012 - Am Heart Assoc
Background—Atrial tissue fibrosis is often an important component of the atrial fibrillation
(AF) substrate. Small noncoding microRNAs are important mediators in many cardiac …
(AF) substrate. Small noncoding microRNAs are important mediators in many cardiac …
microRNAs in cardiovascular disease–clinical application
Abstract microRNAs (miRNAs) are well-known, powerful regulators of gene expression, and
their potential to serve as circulating biomarkers is widely accepted. In cardiovascular …
their potential to serve as circulating biomarkers is widely accepted. In cardiovascular …
Regulation of the SK3 channel by microRNA-499—potential role in atrial fibrillation
TY Ling, XL Wang, Q Chai, TW Lau, CM Koestler… - Heart Rhythm, 2013 - Elsevier
BACKGROUND: MicroRNAs are important regulators of gene expression, including those
involving electrical remodeling in atrial fibrillation (AF). Recently, KCNN3, the gene that …
involving electrical remodeling in atrial fibrillation (AF). Recently, KCNN3, the gene that …