The physics of proton therapy

WD Newhauser, R Zhang - Physics in Medicine & Biology, 2015 - iopscience.iop.org
The physics of proton therapy has advanced considerably since it was proposed in 1946.
Today analytical equations and numerical simulation methods are available to predict and …

Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Adaptive proton therapy

H Paganetti, P Botas, GC Sharp… - Physics in Medicine & …, 2021 - iopscience.iop.org
Radiation therapy treatments are typically planned based on a single image set, assuming
that the patient's anatomy and its position relative to the delivery system remains constant …

Roadmap: helium ion therapy

A Mairani, S Mein, E Blakely, J Debus… - Physics in Medicine …, 2022 - iopscience.iop.org
Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

MR-guided proton therapy: a review and a preview

A Hoffmann, B Oborn, M Moteabbed, S Yan… - Radiation …, 2020 - Springer
Background The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is
expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The …

A full-scale clinical prototype for proton range verification using prompt gamma-ray spectroscopy

F Hueso-González, M Rabe, TA Ruggieri… - Physics in Medicine …, 2018 - iopscience.iop.org
We present a full-scale clinical prototype system for in vivo range verification of proton pencil-
beams using the prompt gamma-ray spectroscopy method. The detection system consists of …

[图书][B] Monte Carlo techniques in radiation therapy

J Seco, F Verhaegen - 2013 - api.taylorfrancis.com
Monte Carlo simulation techniques made a slow entry in the field of radiotherapy in the late
1970s. Since then they have gained enormous popularity, judging by the number of papers …

First clinical investigation of cone beam computed tomography and deformable registration for adaptive proton therapy for lung cancer

C Veiga, G Janssens, CL Teng, T Baudier… - International Journal of …, 2016 - Elsevier
Purpose An adaptive proton therapy workflow using cone beam computed tomography
(CBCT) is proposed. It consists of an online evaluation of a fast range-corrected dose …

Reoptimization of intensity modulated proton therapy plans based on linear energy transfer

J Unkelbach, P Botas, D Giantsoudi… - International Journal of …, 2016 - Elsevier
Purpose We describe a treatment plan optimization method for intensity modulated proton
therapy (IMPT) that avoids high values of linear energy transfer (LET) in critical structures …

Dose calculation algorithms for external radiation therapy: an overview for practitioners

F De Martino, S Clemente, C Graeff, G Palma, L Cella - Applied sciences, 2021 - mdpi.com
Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …