During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …

Injured peripheral nerves but not central nerves have the capacity to regenerate and
reinnervate their target organs. After the two most severe peripheral nerve injuries of six …

Neurons of the mammalian central nervous system fail to regenerate. Substantial progress
has been made toward identifying the cellular and molecular mechanisms that underlie …

Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …

Primary somatosensory neurons are specialized to transmit specific types of sensory
information through differences in cell size, myelination, and the expression of distinct …

Neuronal microenvironment imbalance is associated with successive and irreversible
pathophysiological changes and insufficient functional restoration after peripheral nerve …

Individuals with spinal cord injury (SCI) usually suffer from permanent neurological deficits,
while spontaneous recovery and therapeutic efficacy are limited. Here, we demonstrate that …

Works on lottery ticket hypothesis (LTH) and single-shot network pruning (SNIP) have raised
a lot of attention currently on post-training pruning (iterative magnitude pruning), and before …