The role of selenium in inflammation and immunity: from molecular mechanisms to therapeutic opportunities
Z Huang, AH Rose, PR Hoffmann - Antioxidants & redox signaling, 2012 - liebertpub.com
Abstract Dietary selenium (] Se), mainly through its incorporation into selenoproteins, plays
an important role in inflammation and immunity. Adequate levels of Se are important for …
an important role in inflammation and immunity. Adequate levels of Se are important for …
The influence of selenium on immune responses
PR Hoffmann, MJ Berry - Molecular nutrition & food research, 2008 - Wiley Online Library
Selenium (Se) is a potent nutritional antioxidant that carries out biological effects through its
incorporation into selenoproteins. Given the crucial roles that selenoproteins play in …
incorporation into selenoproteins. Given the crucial roles that selenoproteins play in …
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …
DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …
death, often characterised by circumstances in which cells or tissues do not merely die and …
Oxidative stress indexes for diagnosis of health or disease in humans
MA Sánchez-Rodríguez… - Oxidative medicine and …, 2019 - Wiley Online Library
Oxidative stress (OS) is the imbalance between oxidant and antioxidant molecules, in favor
of oxidants, that causes aging and disease. Many studies have been published that …
of oxidants, that causes aging and disease. Many studies have been published that …
Diet and asthma: nutrition implications from prevention to treatment
K Allan, G Devereux - Journal of the American Dietetic Association, 2011 - Elsevier
Asthma is characterized by lung airway inflammation initiated and perpetuated by an
inappropriate immune response, increased airway responsiveness, and variable airflow …
inappropriate immune response, increased airway responsiveness, and variable airflow …
Zinc metabolism in airway epithelium and airway inflammation: basic mechanisms and clinical targets. A review
PD Zalewski, AQ Truong-Tran, D Grosser… - Pharmacology & …, 2005 - Elsevier
In addition to basic housekeeping roles in metalloenzymes and transcription factors, dietary
zinc (Zn) is an important immunoregulatory agent, growth cofactor, and cytoprotectant with …
zinc (Zn) is an important immunoregulatory agent, growth cofactor, and cytoprotectant with …
Selenium and selenoproteins in prostanoid metabolism and immunity
Selenium (Se) is an essential trace element that functions in the form of the 21st amino acid,
selenocysteine (Sec) in a defined set of proteins. Se deficiency is associated with …
selenocysteine (Sec) in a defined set of proteins. Se deficiency is associated with …
The role of zinc in the pathogenesis of lung disease
Lung diseases, such as asthma, chronic obstructive pulmonary diseases (COPD), and cystic
fibrosis (CF), are among the leading causes of mortality and morbidity globally. They …
fibrosis (CF), are among the leading causes of mortality and morbidity globally. They …
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
Accumulating evidence highlights links between iron regulation and respiratory disease.
Here, we assessed the relationship between iron levels and regulatory responses in clinical …
Here, we assessed the relationship between iron levels and regulatory responses in clinical …