Tumor‐targeting monoclonal antibodies are available for a number of cancer cell types
(over) expressing the corresponding tumor antigens. Such antibodies can limit tumor …

Antigen (Ag)-presenting cells capture or synthesize Ags that are processed into peptides
bound and displayed on the plasma membrane by major histocompatibility complex (MHC) …

Unconjugated monoclonal antibodies (mAbs) have revolutionized the treatment of many
types of cancer. Some of these mAbs promote the clearance of malignant cells via direct …

Viral diseases represent a major public health concerns and ever-present risks for
developing into future pandemics. Antiviral antibody therapeutics, either alone or in …

Understanding the mechanisms underlying cytotoxic immunoglobulin G (IgG) activity is
critical for improving therapeutic antibody activity and inhibiting autoantibody-mediated …

Schistosoma parasites, causing schistosomiasis, exhibit typical host specificity in host
preference. Many mammals, including humans, are susceptible to infection, while the widely …

Immune cell phenotyping frequently detects lineage-unrelated receptors. Here, we report
that surface receptors can be transferred from primary macrophages to CD4 T cells and …

Numerous antibody-drug conjugates (ADC) are being developed for cancer immunotherapy.
Although several of these agents have demonstrated considerable clinical efficacy and have …

Background In non-small cell lung cancer (NSCLC), the epidermal growth factor receptor
(EGFR) mutation is a representative oncogenic driver mutation. Only about 12% of EGFR …

Trogocytosis is a process in which receptors on acceptor cells remove and internalize
cognate ligands from donor cells. Trogocytosis has a profound and negative impact on mAb …