Chronic myeloid leukemia—advances in biology and new approaches to treatment

JM Goldman, JV Melo - New England Journal of Medicine, 2003 - Mass Medical Soc
An extraordinary series of discoveries about chronic myeloid leukemia (CML) has made this
disease a model of the way in which bench and bedside research can unite and culminate …

How I treat chronic myeloid leukemia in the imatinib era

JM Goldman - Blood, The Journal of the American Society of …, 2007 - ashpublications.org
Although it is now generally accepted that imatinib is the best initial treatment for patients
newly diagnosed with chronic myeloid leukemia (CML) in chronic phase, a number of …

Outcomes of reduced-intensity transplantation for chronic myeloid leukemia: an analysis of prognostic factors from the Chronic Leukemia Working Party of the EBMT

C Crawley, R Szydlo, M Lalancette, A Bacigalupo… - Blood, 2005 - ashpublications.org
This study reports outcomes of allogeneic hematopoietic stem cell transplantation with
reduced-intensity conditioning (RIC) in 186 patients with chronic myeloid leukemia (CML) …

Chimerism and outcomes after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning

F Baron, BM Sandmaier - Leukemia, 2006 - nature.com
Allogeneic hematopoietic cell transplantation (HCT) following nonmyeloablative
conditioning has been extensively evaluated in patients with hematologic malignancies who …

[HTML][HTML] Chimerism analysis within 6 months of allogeneic stem cell transplantation predicts relapse in acute myeloid leukemia

C Huisman, RA De Weger, L De Vries… - Bone marrow …, 2007 - nature.com
The role of chimerism analysis as a prognostic indicator of relapse after hematopoietic stem
cell transplantation (SCT) is controversial. We monitored chimerism status by short tandem …

Allogeneic hematopoietic stem cell transplantation: state of the art and new perspectives

O RingdÉN, K Le Blanc - Apmis, 2005 - Wiley Online Library
Allogeneic hematopoietic stem cell transplantation (ASCT) is a well‐established therapy for
leukemias and other immunohematopoietic disorders. In more recent years, bone marrow as …

Acute kidney injury following HCT: incidence, risk factors and outcome

JA Lopes, S Jorge - Bone marrow transplantation, 2011 - nature.com
Acute kidney injury (AKI) is a common complication in haematopoietic cell transplantation
(HCT) patients and it adversely affects outcome. Herein, we provide a comprehensive and …

Chronic myeloid leukemia: current application of cytogenetics and molecular testing for diagnosis and treatment

A Tefferi, GW Dewald, ML Litzow, J Cortes… - Mayo Clinic …, 2005 - Elsevier
Chronic myeloid leukemia provides an illustrative disease model for both molecular
pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal …

Contemporary analysis of the influence of acute kidney injury after reduced intensity conditioning haematopoietic cell transplantation on long-term survival

JA Lopes, S Gonçalves, S Jorge, M Raimundo… - Bone marrow …, 2008 - nature.com
We evaluated retrospectively the incidence of acute kidney injury (AKI), defined by risk,
injury, failure, loss and end-stage kidney disease (RIFLE) and its influence on long-term …

Early and late-onset acute GvHD following hematopoietic cell transplantation: CT features of gastrointestinal involvement with clinical and pathological correlation

H Brodoefel, W Bethge, M Vogel, M Fenchel… - European journal of …, 2010 - Elsevier
OBJECTIVE: With the introduction of non-myeloablative hematopoietic cell transplantation,
acute graft-versus-host-disease (GvHD) is frequently observed beyond the traditional 100 …