Abstract Purposeof Review Head and neck cancer (HNC) comprises a group of
malignancies, amongst which squamous cell carcinoma accounts for more than 90% of the …

Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

Programmed cell death ligand-1 (PD-L1) binds PD-1 on CD8+ lymphocytes, inhibiting their
cytotoxic action. Its aberrant expression by head and neck squamous cell carcinoma …

The treatment of unresectable or metastatic Head and Neck Squamous Cell Carcinoma
(HNSCC) has traditionally relied on chemotherapy or radiotherapy, yielding suboptimal …

Simple Summary The programmed death-1 receptor monoclonal antibody treatments
pembrolizumab and nivolumab have been successful in the treatment of recurrent or …

Non-melanoma skin cancer (NMSC) is a tumor that arises from human keratinocytes,
showing abnormal control of cell proliferation and aberrant stratification. Cutaneous basal …

Inflammation is an etiological factor of various chronic diseases contributing to more than
50% of worldwide deaths. In this study, we focus on the immunosuppressive role of the …

Although there have been some advances during in recent decades, the treatment of head
and neck squamous cell carcinoma (HNSCC) remains challenging. Resistance is a major …

Approximately 5–20% of HNSCC patients experience second primary cancers within the first
5 years of treatment, contributing to high mortality rates. Epidemiological evidence has …

Purpose Human papilloma virus (HPV) positive head and neck squamous cell carcinoma
(HNSCC) tumors respond significantly better to anticancer treatments. It is assumed to be …