[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

[HTML][HTML] Strategies to prolong the residence time of drug delivery systems on ocular surface

B Grassiri, Y Zambito, A Bernkop-Schnürch - Advances in colloid and …, 2021 - Elsevier
Ocular diseases may be treated via different routes of administration, such as topical,
intracameral, intravitreal, oral and parenteral. Among them the topical route is most accepted …

Nanotechnology for topical drug delivery to the anterior segment of the eye

A Vaneev, V Tikhomirova, N Chesnokova… - International journal of …, 2021 - mdpi.com
Topical drug delivery is one of the most challenging aspects of eye therapy. Eye drops are
the most prevalent drug form, especially for widely distributed anterior segment eye …

[HTML][HTML] Nanomedicines: redefining traditional medicine

W Lu, J Yao, X Zhu, Y Qi - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Nanomedicines offer nanoscale drug delivery system. They offer ways of promising drug
transportation, and address the issues of lack of targeting and permeability of traditional …

Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update

M Afarid, S Mahmoodi, R Baghban - Journal of Nanobiotechnology, 2022 - Springer
Ocular drug delivery is one of the most challenging endeavors among the various available
drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic …

How can machine learning and multiscale modeling benefit ocular drug development?

N Wang, Y Zhang, W Wang, Z Ye, H Chen, G Hu… - Advanced Drug Delivery …, 2023 - Elsevier
The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …

Aflibercept Loaded Eye‐Drop Hydrogel Mediated with Cell‐Penetrating Peptide for Corneal Neovascularization Treatment

J Zhou, Y Cai, T Li, H Zhou, H Dong, X Wu, Z Li… - Small, 2024 - Wiley Online Library
Corneal neovascularization (CoNV) is a major cause of visual impairment worldwide.
Currently, available treatment options have limited efficacy and are associated with adverse …

A review on albumin as a biomaterial for ocular drug delivery

R Tiwari, NK Sethiya, AS Gulbake, NK Mehra… - International Journal of …, 2021 - Elsevier
Abstract Development of ocular drug delivery system is one of the most technically
challenging tasks, when compared with other routes of drug delivery. Eye (an intricate …