The Chemistry of Neutron Capture Therapy. (Chem. Rev. 1998, 98, 1515. Published on the Web May 20, 1998)
AH Soloway, W Tjarks, BA Barnum, FG Rong… - Chemical …, 1998 - ACS Publications
Brain cancer diagnosis and therapy with nanoplatforms
YEL Koo, GR Reddy, M Bhojani, R Schneider… - Advanced drug delivery …, 2006 - Elsevier
Treatment of brain cancer remains a challenge despite recent improvements in surgery and
multimodal adjuvant therapy. Drug therapies of brain cancer have been particularly …
multimodal adjuvant therapy. Drug therapies of brain cancer have been particularly …
Chemotherapy of glioblastoma in rats using doxorubicin‐loaded nanoparticles
SCJ Steiniger, J Kreuter, AS Khalansky… - … Journal of Cancer, 2004 - Wiley Online Library
Glioblastomas belong to the most aggressive human cancers with short survival times. Due
to the blood‐brain barrier, they are mostly inaccessible to traditional chemotherapy. We …
to the blood‐brain barrier, they are mostly inaccessible to traditional chemotherapy. We …
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study
Background Temsirolimus (CCI-779) is a small-molecule inhibitor of the mammalian target
of rapamycin (mTOR) and represents a rational therapeutic target against glioblastoma …
of rapamycin (mTOR) and represents a rational therapeutic target against glioblastoma …
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas
✓ Malignant gliomas have been difficult to treat with chemotherapy. The most effective
agent, BCNU (carmustine), has considerable systemic toxicity and a short half-life in serum …
agent, BCNU (carmustine), has considerable systemic toxicity and a short half-life in serum …
Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study
S Valtonen, U Timonen, P Toivanen, H Kalimo… - …, 1997 - journals.lww.com
OBJECTIVE: To find out the effect of carmustine (bischloroethyl-nitrosourea) combined with
a biodegradable polymer in the treatment of malignant (Grades III and IV) gliomas, applied …
a biodegradable polymer in the treatment of malignant (Grades III and IV) gliomas, applied …
Paclitaxel nanoparticles for the potential treatment of brain tumors
JM Koziara, PR Lockman, DD Allen… - Journal of controlled …, 2004 - Elsevier
Despite the advances in tumor therapy, patients with primary brain tumors and brain
metastases have a very poor prognosis. Low responses to chemotherapy are mainly …
metastases have a very poor prognosis. Low responses to chemotherapy are mainly …
Targeted therapy for brain tumours
MS Lesniak, H Brem - Nature reviews Drug discovery, 2004 - nature.com
Although previously considered untreatable, brain tumours no longer carry the same
prognosis as they did even a decade ago. Recent advances in drug delivery to the central …
prognosis as they did even a decade ago. Recent advances in drug delivery to the central …
Irinotecan therapy in adults with recurrent or progressive malignant glioma
HS Friedman, WP Petros, AH Friedman… - Journal of Clinical …, 1999 - ascopubs.org
PURPOSE: To determine the activity, toxicity, and pharmacokinetics of irinotecan (CPT-11,
Camptosar; Pharmacia & Upjohn, Kalamazoo, MI) in the treatment of adults with …
Camptosar; Pharmacia & Upjohn, Kalamazoo, MI) in the treatment of adults with …
Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience
FJ Attenello, D Mukherjee, G Datoo, MJ McGirt… - Annals of surgical …, 2008 - Springer
Background Gliadel (polifeprosan 20 with carmustine [BCNU] implant) is commonly used for
local delivery of BCNU to high-grade gliomas after resection and is associated with …
local delivery of BCNU to high-grade gliomas after resection and is associated with …