Exploring the Pathophysiology of Long COVID: The Central Role of Low-Grade Inflammation and Multisystem Involvement

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2024 - mdpi.com
Long COVID (LC), also referred to as Post COVID-19 Condition, Post-Acute Sequelae of
SARS-CoV-2 Infection (PASC), and other terms, represents a complex multisystem disease …

Body composition and cardiorespiratory fitness of overweight COVID-19 survivors in different severity degrees: A cohort study

VAS Perli, AF Sordi, MM Lemos, JSA Fernandes… - Scientific Reports, 2023 - nature.com
COVID-19 sequelae are varied, and whether they are temporary or permanent is still
unknown. Identifying these sequelae may guide therapeutic strategies to improve these …

Mechanisms underlying exercise intolerance in long COVID: An accumulation of multisystem dysfunction

A Jamieson, L Al Saikhan, L Alghamdi… - Physiological …, 2024 - Wiley Online Library
The pathogenesis of exercise intolerance and persistent fatigue which can follow an
infection with the SARS‐CoV‐2 virus (“long COVID”) is not fully understood. Cases were …

[HTML][HTML] Physical Exercise-related Manifestations of long COVID: A Systematic Review and Meta-Analysis

C Zheng, JJ Chen, ZH Dai, KW Wan, FH Sun… - Journal of Exercise …, 2024 - Elsevier
Objective This study aims to systematically assess physical exercise-related symptoms of
post-acute sequelae of SARS-CoV-2 infection (PASC or long COVID) in coronavirus disease …

[HTML][HTML] Effect of physical activity on long COVID fatigue: an unsolved enigma

F Coscia, ES Di Filippo, PV Gigliotti… - European Journal of …, 2023 - ncbi.nlm.nih.gov
COVID-19 disease is well documented and often the most common symptoms include
myalgia and muscle fatigue. Approximately 10% of those infected complain of persistent …

Normobaric hypoxia shows enhanced FOXO1 signaling in obese mouse gastrocnemius muscle linked to metabolism and muscle structure and neuromuscular …

J Song, LPM Duivenvoorde, S Grefte, O Kuda… - … -European Journal of …, 2023 - Springer
Skeletal muscle relies on mitochondria for sustainable ATP production, which may be
impacted by reduced oxygen availability (hypoxia). Compared with long-term hypoxia, the …

Maximal oxidative capacity during exercise is associated with muscle power output in patients with long coronavirus disease 2019 (COVID-19) syndrome. A …

R Ramírez-Vélez, S Oscoz-Ochandorena… - Clinical Nutrition …, 2023 - Elsevier
Background & aims Long COVID syndrome (LCS) involves persistent symptoms
experienced by many patients after recovering from coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Using the ClinFIT COVID-19 Instrument to Assess the Functional Impairments Specific to Post-COVID-19 Patients in Romania

C Ursescu, G Teodoru, S Bucurica, RI Nica, ȘD Lazăr… - Diagnostics, 2024 - mdpi.com
Introduction: The COVID-19 pandemic has led to approximately 3.5 million cases in
Romania, causing systemic inflammation and over 200 symptoms affecting various body …

[HTML][HTML] Motor and Respiratory Tele-Rehabilitation in Patients with Long COVID-19 after Hospital Discharge: An Interventional Study

S Cerfoglio, F Verme, P Capodaglio, P Rossi… - Life, 2024 - ncbi.nlm.nih.gov
The persistence of symptoms following COVID-19 infection represents a significant
challenge in healthcare management. During the outbreak, tele-rehabilitation emerged as a …

Gastrocnemius electrical stimulation increases ankle dorsiflexion strength in patients with post-acute sequelae of SARS-COV-2 (PASC): a double-blind randomized …

M Lee, A Zulbaran-Rojas, M Bargas-Ochoa… - Scientific Reports, 2024 - nature.com
Post-Acute sequelae of SARS-CoV-2 (PASC) is a multisystem disorder causing persistent
musculoskeletal deconditioning and reduced lower extremity strength. Electrical stimulation …