Osteoarthritis (OA) has a considerable hereditary component and is considered to be a
polygenic disease. Data derived from genetic analyses and genome-wide screening of …

Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment
options. Pet dogs share both an environment and lifestyle attributes with their owners, and a …

The domestic dog is becoming an increasingly valuable model species in medical genetics,
showing particular promise to advance our understanding of cancer and orthopaedic …

Genome-Wide Association Studies shed light on the identification of genes underlying
human diseases and agriculturally important traits. This potential has been shadowed by …

Background The inheritance of most human diseases and agriculturally important traits is
controlled by many genes with small effects. Identifying these genes, while simultaneously …

Canine hip dysplasia (CHD) is a polygenic and multifactorial developmental disorder
characterized by coxofemoral (hip) joint laxity, degeneration, and osteoarthritis (OA). Current …

Osteoarthritis, or degenerative joint disease, is characterized by a complex progressive
imbalance between cartilage production and degradation. The inciting biochemical cause of …

Drought resistance is an important breeding target for enhancing alfalfa productivity in arid
and semi-arid regions. Identification of genes involved in drought tolerance will facilitate …

Considerable clinical and molecular variations have been known in retinal blinding
diseases in man and also in dogs. Different forms of retinal diseases occur in specific breed …

Advances in DNA sequencing and other technologies have greatly facilitated the
identification of genetic risk factors for inherited diseases in dogs. We review recent …