Gender-specific care of the patient with diabetes: review and recommendations
BACKGROUND:: Men and women differ in their experience of diabetes mellitus (DM). For
optimal prevention and treatment of the disease, these differences must be acknowledged …
optimal prevention and treatment of the disease, these differences must be acknowledged …
Interplay between type 1 diabetes mellitus and celiac disease: implications in treatment
Background: A complex interplay between genetic and environmental factors contributes to
disease etiology of most of the autoimmune disorders. Type 1 diabetes mellitus (T1DM) and …
disease etiology of most of the autoimmune disorders. Type 1 diabetes mellitus (T1DM) and …
The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression
Mutations in the gene autoimmune regulator (AIRE) cause autoimmune polyendocrinopathy
candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells …
candidiasis ectodermal dystrophy. AIRE is expressed in thymic medullary epithelial cells …
Maternal antibiotic treatment protects offspring from diabetes development in nonobese diabetic mice by generation of tolerogenic APCs
Y Hu, J Peng, N Tai, C Hu, X Zhang… - The Journal of …, 2015 - journals.aai.org
Abstract Type 1 diabetes (T1D) is a T cell–mediated autoimmune disease that involves the
slow, progressive destruction of islet β cells and loss of insulin production, as a result of …
slow, progressive destruction of islet β cells and loss of insulin production, as a result of …
Different immunological responses to early-life antibiotic exposure affecting autoimmune diabetes development in NOD mice
Y Hu, P Jin, J Peng, X Zhang, FS Wong, L Wen - Journal of autoimmunity, 2016 - Elsevier
Environmental factors clearly influence the pathogenesis of Type 1 diabetes, an
autoimmune disease. We have studied gut microbiota as important environmental agents …
autoimmune disease. We have studied gut microbiota as important environmental agents …
A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes
B Phillips, K Nylander, J Harnaha, J Machen… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—This study was aimed at ascertaining the efficacy of antisense oligonucleotide-
formulated microspheres to prevent type 1 diabetes and to reverse new-onset disease …
formulated microspheres to prevent type 1 diabetes and to reverse new-onset disease …
New‐onset type 1 diabetes and severe acute respiratory syndrome coronavirus 2 infection
Abstract Type 1 diabetes (T1D) is a condition characterized by an absolute deficiency of
insulin. Loss of insulin‐producing pancreatic islet β cells is one of the many causes of T1D …
insulin. Loss of insulin‐producing pancreatic islet β cells is one of the many causes of T1D …
Antibiotics, gut microbiota, environment in early life and type 1 diabetes
Y Hu, FS Wong, L Wen - Pharmacological research, 2017 - Elsevier
The gut microbiota interact with innate immune cells and play an important role in shaping
the immune system. Many factors may influence the composition of the microbiota such as …
the immune system. Many factors may influence the composition of the microbiota such as …
Pharmacological targeting of GLUT1 to control autoreactive T cell responses
C Di Dedda, D Vignali, L Piemonti, P Monti - International Journal of …, 2019 - mdpi.com
An increasing body of evidence indicates that bio-energetic metabolism of T cells can be
manipulated to control T cell responses. This potentially finds a field of application in the …
manipulated to control T cell responses. This potentially finds a field of application in the …
The convergence of type 1 and type 2 diabetes in childhood: the accelerator hypothesis
TJ Wilkin - Pediatric diabetes, 2012 - Wiley Online Library
It seems likely that type 1 and type 2 diabetes lie at different points of the same spectrum,
separated by the misunderstanding that one belongs to childhood and the other to …
separated by the misunderstanding that one belongs to childhood and the other to …