This article summarizes the likely benefits of melatonin in the attenuation of COVID-19
based on its putative pathogenesis. The recent outbreak of COVID-19 has become a …

Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

Diabetes mellitus is a major cause of blindness and chronic ulcers in the working age
population worldwide. Former research have found that differentially expressed circular …

Rheumatoid arthritis (RA) is an inflammatory disease that begins with a loss of tolerance to
modified self-antigens and immune system abnormalities, eventually leading to synovitis …

Angiogenesis depends on proangiogenic and anti-angiogenic molecules that regulate
endothelial cell proliferation and migration. Well-regulated angiogenesis plays a pivotal role …

Checkpoint inhibitors, such as anti-PD-1/PD-L1 antibodies, have been shown to be
extraordinarily effective, but their durable response rate remains low, especially in colorectal …

Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus
(DM) causing vision impairment even at young ages. There are numerous mechanisms …

Background Chronic inflammatory conditions like obesity may adversely impact the
biological functions underlying the regenerative potential of mesenchymal stromal/stem cells …

Cancer is one of the greatest causes of death worldwide. With the development of surgery,
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …

The recent pandemic of COVID-19 has already infected millions of individuals and has
resulted in the death of hundreds of thousands worldwide. Based on clinical features …