[HTML][HTML] Extracellular Vesicles as Drug Delivery Systems in Organ Transplantation: The Next Frontier
HVM Spiers, LKJ Stadler, H Smith, V Kosmoliaptsis - Pharmaceutics, 2023 - mdpi.com
Extracellular vesicles are lipid bilayer-delimited nanoparticles excreted into the extracellular
space by all cells. They carry a cargo rich in proteins, lipids and DNA, as well as a full …
space by all cells. They carry a cargo rich in proteins, lipids and DNA, as well as a full …
Liver disease and cell therapy: advances made and remaining challenges
S Khan, S Mahgoub, N Fallatah, PF Lalor… - Stem Cells, 2023 - academic.oup.com
The limited availability of organs for liver transplantation, the ultimate curative treatment for
end stage liver disease, has resulted in a growing and unmet need for alternative therapies …
end stage liver disease, has resulted in a growing and unmet need for alternative therapies …
Novel approaches to characterize individual drug metabolism and advance precision medicine
Interindividual variability in drug metabolism can significantly affect drug concentrations in
the body and subsequent drug response. Understanding an individual's drug metabolism …
the body and subsequent drug response. Understanding an individual's drug metabolism …
Exosomes in chronic liver disease
PB Mohan, S Rajpurohit, B Musunuri, G Bhat… - Clinica Chimica …, 2023 - Elsevier
Chronic liver disease (CLD) is the major cause of mortality and morbidity, particularly in
developing countries. Although there has been a significant advancement in the …
developing countries. Although there has been a significant advancement in the …
[HTML][HTML] The emerging role of extracellular vesicles and autophagy machinery in NASH—Future horizons in NASH management
EM Trifylli, AG Kriebardis, E Koustas… - International Journal of …, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is considered the most frequent chronic hepatic
disease in the general population, while it is the first cause of liver transplantation in the US …
disease in the general population, while it is the first cause of liver transplantation in the US …
A narrative review of the role of exosomes and caveolin-1 in liver diseases and cancer
X Jiang, S Wu, C Hu - International Immunopharmacology, 2023 - Elsevier
Abstract Exosomes are nanoscale (40–100 nm) vesicles secreted by different types of cells
and have attracted extensive interest in recent years because of their unique role in disease …
and have attracted extensive interest in recent years because of their unique role in disease …
[HTML][HTML] Comprehensive strategy for identifying extracellular vesicle surface proteins as biomarkers for non-alcoholic fatty liver disease
NA Garcia, M Mellergaard, H Gonzalez-King… - International Journal of …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a liver disorder that has become a global health
concern due to its increasing prevalence. There is a need for reliable biomarkers to aid in …
concern due to its increasing prevalence. There is a need for reliable biomarkers to aid in …
[HTML][HTML] Plasma Pattern of Extracellular Vesicles Isolated from Hepatitis C Virus Patients and Their Effects on Human Vascular Endothelial Cells
E Grossini, C Smirne, S Venkatesan, S Tonello… - International Journal of …, 2023 - mdpi.com
Hepatitis C virus (HCV) patients are at increased risk of cardiovascular disease (CVD). In
this study, we aimed to evaluate the role of extracellular vesicles (EVs) as pathogenic factors …
this study, we aimed to evaluate the role of extracellular vesicles (EVs) as pathogenic factors …
Survey of organ‐derived small extracellular vesicles and particles (sEVPs) to identify selective protein markers in mouse serum
K Abdelmohsen, AB Herman, AE Carr… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles and particles (EVPs) are secreted by organs across the body into
different circulatory systems, including the bloodstream, and reflect pathophysiologic …
different circulatory systems, including the bloodstream, and reflect pathophysiologic …
[HTML][HTML] Extracellular Vesicles as Delivery Vehicles for Non-Coding RNAs: Potential Biomarkers for Chronic Liver Diseases
A Ferro, G Saccu, S Mattivi, A Gaido… - Biomolecules, 2024 - mdpi.com
In recent years, EVs have emerged as promising vehicles for coding and non-coding RNAs
(ncRNAs), which have demonstrated remarkable potential as biomarkers for various …
(ncRNAs), which have demonstrated remarkable potential as biomarkers for various …