Impedance rhythms in human limbic system

F Mivalt, V Kremen, V Sladky, J Cui… - Journal of …, 2023 - Soc Neuroscience
The impedance is a fundamental electrical property of brain tissue, playing a crucial role in
shaping the characteristics of local field potentials, the extent of ephaptic coupling, and the …

Cues for seizure timing

VR Rao, MG Leguia, TK Tcheng, MO Baud - Epilepsia, 2021 - Wiley Online Library
The cyclical organization of seizures in epilepsy has been described since antiquity.
However, historical explanations for seizure cycles—based on celestial, hormonal, and …

NREM sleep is the state of vigilance that best identifies the epileptogenic zone in the interictal electroencephalogram

P Klimes, J Cimbalnik, M Brazdil, J Hall, F Dubeau… - …, 2019 - Wiley Online Library
Objective Interictal epileptiform anomalies such as epileptiform discharges or high‐
frequency oscillations show marked variations across the sleep‐wake cycle. This study …

Gauging seizure risk

MO Baud, VR Rao - Neurology, 2018 - AAN Enterprises
The current paradigm for treatment of epilepsy begins with trials of antiepileptic drugs,
followed by evaluation for resective brain surgery in drug-resistant patients. If surgery is not …

No evidence for critical slowing down prior to human epileptic seizures

T Wilkat, T Rings, K Lehnertz - Chaos: An Interdisciplinary Journal of …, 2019 - pubs.aip.org
There is an ongoing debate whether generic early warning signals for critical transitions
exist that can be applied across diverse systems. The human epileptic brain is often …

SleepSEEG: automatic sleep scoring using intracranial EEG recordings only

N von Ellenrieder, L Peter-Derex… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. To perform automatic sleep scoring based only on intracranial
electroencephalography (iEEG), without the need for scalp EEG), electrooculography (EOG) …

Computational modeling allows unsupervised classification of epileptic brain states across species

I Dallmer-Zerbe, N Jajcay, J Chvojka, R Janca… - Scientific Reports, 2023 - nature.com
Current advances in epilepsy treatment aim to personalize and responsively adjust
treatment parameters to overcome patient heterogeneity in treatment efficiency. For tailoring …

Closed-loop neurostimulation for the treatment of psychiatric disorders

KK Sellers, JL Cohen, AN Khambhati, JM Fan… - …, 2024 - nature.com
Despite increasing prevalence and huge personal and societal burden, psychiatric diseases
still lack treatments which can control symptoms for a large fraction of patients. Increasing …

Epilepsy personal assistant device—A mobile platform for brain state, dense behavioral and physiology tracking and controlling adaptive stimulation

T Pal Attia, D Crepeau, V Kremen, M Nasseri… - Frontiers in …, 2021 - frontiersin.org
Epilepsy is one of the most common neurological disorders, and it affects almost 1% of the
population worldwide. Many people living with epilepsy continue to have seizures despite …

Epilepsy and its interaction with sleep and circadian rhythm

B Jin, T Aung, Y Geng, S Wang - Frontiers in Neurology, 2020 - frontiersin.org
Growing evidence shows the bidirectional interactions between sleep, circadian rhythm, and
epilepsy. Comprehending how these interact with each other may help to advance our …