Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …

Primary open angle glaucoma (POAG) is a complex progressive optic nerve neuropathy
triggered by both environmental and genetic risk factors. Several ocular tissues, including …

Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …

Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is
used to diagnose and manage ophthalmic diseases including glaucoma. We present the …

Epidemiological studies suggest that by 2020 the prevalence of primary open angle
glaucoma (POAG) is estimated to increase to 76.0 million, and to 111.8 million by 2040 …

Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness
worldwide, disproportionately affects individuals of African ancestry. We conducted a …

Purpose.: Multiple genes have been associated with primary open angle glaucoma (POAG)
in Caucasian populations. We now examine the association of these loci in populations of …

Background No opioid receptor, mu 1 (OPRM1) gene polymorphisms, including the
functional single nucleotide polymorphism (SNP) rs1799971, have been conclusively …

Abstract The European Eye Epidemiology (E3) consortium is a recently formed consortium
of 29 groups from 12 European countries. It already comprises 21 population-based studies …

Purpose.: We investigated the association of genetic factors with primary open angle
glaucoma (POAG), including high tension glaucoma (HTG) and normal tension glaucoma …