A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

[HTML][HTML] Tissue stem cells: architects of their niches

E Fuchs, HM Blau - Cell stem cell, 2020 - cell.com
Stem cells (SCs) maintain tissue homeostasis and repair wounds. Despite marked variation
in tissue architecture and regenerative demands, SCs often follow similar paradigms in …

[HTML][HTML] The jam session between muscle stem cells and the extracellular matrix in the tissue microenvironment

M Loreti, A Sacco - NPJ Regenerative medicine, 2022 - nature.com
Skeletal muscle requires a highly orchestrated coordination between multiple cell types and
their microenvironment to exert its function and to maintain its homeostasis and regenerative …

[HTML][HTML] Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing

J Ishihara, A Ishihara, K Fukunaga, K Sasaki… - Nature …, 2018 - nature.com
Laminin, as a key component of the basement membrane extracellular matrix (ECM),
regulates tissue morphogenesis. Here, we show that multiple laminin isoforms …

[HTML][HTML] Shaping synapses by the neural extracellular matrix

M Ferrer-Ferrer, A Dityatev - Frontiers in neuroanatomy, 2018 - frontiersin.org
Accumulating data support the importance of interactions between pre-and postsynaptic
neuronal elements with astroglial processes and extracellular matrix (ECM) for formation …

[HTML][HTML] Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche

SC Schüler, Y Liu, S Dumontier… - Frontiers in Cell and …, 2022 - frontiersin.org
The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …

The influence of circular RNAs on autophagy and disease progression

Y Wang, Y Mo, M Peng, S Zhang, Z Gong, Q Yan… - Autophagy, 2022 - Taylor & Francis
Circular RNAs (circRNAs) are non-coding RNAs that have attracted considerable attention
in recent years. Owing to their distinct circular structure, circRNAs are stable in cells …

[HTML][HTML] Myostatin and its regulation: a comprehensive review of myostatin inhibiting strategies

MH Baig, K Ahmad, JS Moon, SY Park… - Frontiers in …, 2022 - frontiersin.org
Myostatin (MSTN) is a well-reported negative regulator of muscle growth and a member of
the transforming growth factor (TGF) family. MSTN has important functions in skeletal muscle …

New concepts in basement membrane biology

W Halfter, P Oertle, CA Monnier, L Camenzind… - The FEBS …, 2015 - Wiley Online Library
Basement membranes (BMs) are thin sheets of extracellular matrix that outline epithelia,
muscle fibers, blood vessels and peripheral nerves. The current view of BM structure and …

The muscle stem cell niche in health and disease

O Mashinchian, A Pisconti, E Le Moal… - Current topics in …, 2018 - Elsevier
The regulation of stem cells that maintain and regenerate postnatal tissues depends on
extrinsic signals originating from their microenvironment, commonly referred to as the stem …