VSV-EBOV is a replication-competent Ebola virus (EBOV) vaccine, which was tested in
clinical trials as response to the Ebola virus disease (EVD) outbreak 2013–2016. It is the …

A pathogen-based approach to infectious disease diagnosis has long been the gold
standard, despite poor sensitivity, specificity, or long time to result with this method. The host …

Antibiotic treatment of tuberculosis takes at least 6 months, putting a major burden on
patients and health systems in large parts of the world. Treatment beyond two months is …

Tuberculosis is a complex disease, which can affect many organs other than the lungs. Initial
infection may be cleared without inducing immunological memory, or progress directly to …

Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently
needed. We developed a robust and simple, PCR-based host-blood transcriptomic …

Background Tuberculosis (TB) remains one of the leading causes of death in the world.
Targeted treatment to prevent progression from TB exposure and infection to disease is a …

Transcriptional responses to adjuvanted vaccines can vary substantially among populations.
Interindividual diversity in levels of pathogen exposure, and thus of cell-mediated …

Tuberculosis is one of the most ancient diseases known to affect humans and according to
WHO remains major cause of death after HIV/AIDS. It remains a global public health …

Tuberculosis (TB) is a contagious disease which is among the top 10 causes of death in the
world. In order to eliminate the disease by 2050, the treatment of TB infection (TBI) is …

Dit artikel geeft een overzicht van de richtlijnen uit 2018 voor de kortere behandeling van
latente Mycobacterium tuberculosis-infectie (LTBI), opgesteld door de …