[HTML][HTML] Mpox (formerly monkeypox): pathogenesis, prevention, and treatment

J Lu, H Xing, C Wang, M Tang, C Wu, F Ye… - … and Targeted Therapy, 2023 - nature.com
In 2022, a global outbreak of Mpox (formerly monkeypox) occurred in various countries
across Europe and America and rapidly spread to more than 100 countries and regions. The …

An MPXV mRNA-LNP vaccine candidate elicits protective immune responses against monkeypox virus

Y Tian, M Li, Y Yang, C Li, Y Peng, H Yang… - Chinese Chemical …, 2024 - Elsevier
The monkeypox virus (MPXV) outbreak, declared a Public Health Emergency of
International Concern (PHEIC) by the World Health Organization (WHO) in 2022, continues …

[HTML][HTML] Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses

H Chi, SQ Zhao, RY Chen, XX Suo, RR Zhang… - … and Targeted Therapy, 2024 - nature.com
The Orthopoxvirus genus, especially variola virus (VARV), monkeypox virus (MPXV),
remains a significant public health threat worldwide. The development of therapeutic …

Various mpox recombinant subunits induce broadly reactive antibodies against orthopoxvirus in mice

Y Jiang, Z Ren, Y Yang, J Chen… - Journal of medical …, 2023 - pubmed.ncbi.nlm.nih.gov
Various mpox recombinant subunits induce broadly reactive antibodies against orthopoxvirus
in mice Various mpox recombinant subunits induce broadly reactive antibodies against …

Screening, expression and identification of nanobody against monkeypox virus A35R

N Meng, X Cheng, M Sun, Y Zhang, X Sun… - International Journal …, 2023 - Taylor & Francis
Introduction The monkeypox (Mpox) virus epidemic presents a significant risk to global
public health security. A35R, a crucial constituent of EEV, plays a pivotal role in virus …

Serological methods for the detection of antibodies against monkeypox virus applicable for laboratories with different biosafety levels

M Grossegesse, D Stern, N Hofmann… - Journal of Medical …, 2023 - Wiley Online Library
The monkeypox virus (MPXV) outbreak in 2022 has renewed interest in the detection of
antibodies against orthopox viruses (OPXV) and MPXV, as serological methods can aid …

[HTML][HTML] Immune responses associated with mpox viral clearance in men with and without HIV in Spain: a multisite, observational, prospective cohort study

I Moraes-Cardoso, S Benet, J Carabelli… - The Lancet …, 2024 - thelancet.com
Background Since the emergence of the global mpox outbreak in May, 2022, more than 90
000 cases have been diagnosed across 110 countries, disproportionately affecting people …

Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants

L He, Q Wu, Z Zhang, L Chen, K Yu, L Li… - Molecular …, 2024 - ACS Publications
The continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has evaded the efficacy of previously developed antibodies and vaccines, thus remaining …

[HTML][HTML] Isolation and characterization of mpox virus from the first mpox case in Shenzhen, China

L Cheng, L Yang, M Wang, Y Peng, H Wang… - Virologica …, 2024 - ncbi.nlm.nih.gov
Unlike previous outbreaks of the mpox (previously known as monkeypox), which were
localized in Africa and resulted in small numbers of infections due to limited human-to …

[HTML][HTML] The Generation and Characterization of Monoclonal Antibodies against the MPXV A29L Protein

W Zhu, M Zhang, M Zhang, R Jing, J Zhou, H Cao… - Viruses, 2024 - mdpi.com
Mpox (formerly known as monkeypox) is a zoonotic disease caused by monkeypox virus
(MPXV), a DNA virus belonging to the Orthopoxvirus genus, in the Poxviridae family. The …