Natural products as anticancer agents: current status and future perspectives
A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …
years. Several compounds have been synthesized from natural products by modifying their …
Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response
M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …
Autophagy, a critical element in the aging male reproductive disorders and prostate cancer: a therapeutic point of view
Autophagy is a highly conserved, lysosome-dependent biological mechanism involved in
the degradation and recycling of cellular components. There is growing evidence that …
the degradation and recycling of cellular components. There is growing evidence that …
Nanoparticles induce autophagy via mTOR pathway inhibition and reactive oxygen species generation
L Jia, SL Hao, WX Yang - Nanomedicine, 2020 - Taylor & Francis
Due to their unique physicochemical properties, nanoparticles (NPs) have been increasingly
developed for use in various fields. However, there has been both growing negative …
developed for use in various fields. However, there has been both growing negative …
Tumour dormancy in inflammatory microenvironment: a promising therapeutic strategy for cancer-related bone metastasis
W Hu, L Zhang, Y Dong, Z Tian, Y Chen… - Cellular and Molecular …, 2020 - Springer
Cancer metastasis is a unique feature of malignant tumours. Even bone can become a
common colonization site due to the tendency of solid tumours, including breast cancer …
common colonization site due to the tendency of solid tumours, including breast cancer …
Combination of the NRF2 Inhibitor and Autophagy Inhibitor Significantly Inhibited Tumorigenicity of Castration‐Resistant Prostate Cancer
Y Zhang, Z Xin, B Dong, W Xue - … and Mathematical Methods in …, 2022 - Wiley Online Library
Prostate cancer (PCa) is the most frequent cancer in men. Developing new treatment
methods for CRPC will be a significant challenge in the clinical treatment of PCa. In …
methods for CRPC will be a significant challenge in the clinical treatment of PCa. In …
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo
L Gou, GGL Yue, JKM Lee, PT Puno… - Biochemical …, 2023 - Elsevier
Breast cancer is the most commonly diagnosed cancer among women, and its metastasis to
distant organs accounts for the majority of death. Eriocalyxin B (Eri B), an ent-kaurane …
distant organs accounts for the majority of death. Eriocalyxin B (Eri B), an ent-kaurane …
The impact of icariside II on human prostate cancer cell proliferation, mobility, and autophagy via PI3K-AKT-mTOR signaling pathway
S Li, Y Zhan, Y Xie, Y Wang, Y Liu - Drug Design, Development …, 2020 - Taylor & Francis
Introduction The flavonol glycoside icariside II (ICA II) has been shown to exhibit a range of
anti-tumor properties. Herein, we evaluated the impact of ICA II on human prostate cancer …
anti-tumor properties. Herein, we evaluated the impact of ICA II on human prostate cancer …
Computational identification and experimental validation of potential inhibitors of JAK1 kinase from natural source for the effective treatment of colorectal …
Colorectal cancer (CRC) has become a global threat worldwide with constantly increasing
incidence and mortality rates every year, especially in the US and China. Janus kinase …
incidence and mortality rates every year, especially in the US and China. Janus kinase …
Effect and mechanism of action of SLP‑2 on the apoptosis and autophagy of gastric cancer cells
S Yang, Y Huang, H Zhang, F Wang… - Oncology …, 2021 - spandidos-publications.com
This study was designed to investigate the effect of stomatin‑like protein 2 (SLP‑2) on the
apoptosis and autophagy of gastric cancer cells and its underlying mechanism. The …
apoptosis and autophagy of gastric cancer cells and its underlying mechanism. The …