Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

Epigenetic regulation in human cancer: the potential role of epi-drug in cancer therapy

Y Lu, YT Chan, HY Tan, S Li, N Wang, Y Feng - Molecular cancer, 2020 - Springer
Epigenetics is dynamic and heritable modifications to the genome that occur independently
of DNA sequence. It requires interactions cohesively with various enzymes and other …

The MicroRNA family gets wider: the IsomiRs classification and role

L Tomasello, R Distefano, G Nigita… - Frontiers in cell and …, 2021 - frontiersin.org
MicroRNAs (miRNAs or miRs) are the most characterized class of non-coding RNAs and are
engaged in many cellular processes, including cell differentiation, development, and …

An ultrasensitive miRNA-based genosensor for detection of microRNA 21 in gastric cancer cells based on functional signal amplifier and synthesized perovskite …

P Shahbazi-Derakhshi, E Mahmoudi, MM Majidi… - Biosensors, 2023 - mdpi.com
In the present research work, the state-of-art label-free electrochemical genosensing
platform was developed based on the hybridization process in the presence of [Fe (CN) 6] …

The various regulatory functions of long noncoding RNAs in apoptosis, cell cycle, and cellular senescence

M Heydarnezhad Asl… - Journal of cellular …, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a group of noncoding cellular RNAs involved in
significant biological phenomena such as differentiation, cell development, genomic …

Natural killer cell-derived exosomes for cancer immunotherapy: innovative therapeutics art

Z Hatami, ZS Hashemi, M Eftekhary, A Amiri… - Cancer Cell …, 2023 - Springer
Chimeric antigen receptor natural killer cells (CAR-NK) promote off-the-shelf cellular therapy
for solid tumors and malignancy. However,, the development of CAR-NK is due to their …

Natural bioactive compounds targeting histone deacetylases in human cancers: recent updates

A Bouyahya, N El Hachlafi, T Aanniz, I Bourais… - Molecules, 2022 - mdpi.com
Cancer is a complex pathology that causes a large number of deaths worldwide. Several
risk factors are involved in tumor transformation, including epigenetic factors. These factors …

The emerging role of MicroRNA-182 in tumorigenesis; a promising therapeutic target

P Sameti, M Tohidast, M Amini… - Cancer Cell …, 2023 - Springer
A wide range of studies have indicated that microRNAs (miRNAs), a type of small single-
stranded regulatory RNAs, are dysregulated in a different variety of human cancers …

MicroRNA‐124‐3p suppresses PD‐L1 expression and inhibits tumorigenesis of colorectal cancer cells via modulating STAT3 signaling

E Roshani Asl, Y Rasmi… - Journal of cellular …, 2021 - Wiley Online Library
Programmed death ligand 1 (PD‐L1) plays a significant role in colorectal tumorigenesis
through induction of regulatory T cells (Tregs) and suppression of antitumor immunity …

Biochemical and immunological changes in obesity

B Barakat, MEF Almeida - Archives of Biochemistry and Biophysics, 2021 - Elsevier
Obesity is a syndemia that promotes high expenditures for public health, and is defined by
the excess of adipose tissue that is classified according to its function and anatomical …