Potential microbiological effects of higher dosing of echinocandins

WJ Steinbach, F Lamoth… - Clinical Infectious …, 2015 - academic.oup.com
The antifungal “paradoxical effect” has been described as the reversal of growth inhibition at
high doses of echinocandins, most usually caspofungin. This microbiological effect appears …

Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans

C Fu, N Donadio, ME Cardenas, J Heitman - Genetics, 2018 - academic.oup.com
Abstract The Ca2+/calmodulin-dependent protein phosphatase calcineurin orchestrates
sexual reproduction, stress responses, and virulence via branched downstream pathways in …

Caspofungin: a review of its characteristics, activity, and use in intensive care units

SMR Hashemian, T Farhadi… - Expert Review of Anti …, 2020 - Taylor & Francis
Introduction Candidemia is the fourth frequent reason of healthcare-related bloodstream
infections in critically ill patients. For initial management of (suspected) invasive candidiasis …

In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes

E Dannaoui, P Schwarz… - Antimicrobial agents and …, 2009 - Am Soc Microbiol
The in vitro interaction of antifungals with immunosuppressive drugs was evaluated against
zygomycetes. The combination of amphotericin B with cyclosporine, rapamycin, or …

In Vitro Interactions between Antifungals and Immunosuppressants against Aspergillus fumigatus Isolates from Transplant and Nontransplant Patients

WJ Steinbach, N Singh, JL Miller… - Antimicrobial agents …, 2004 - Am Soc Microbiol
We performed in vitro antifungal checkerboard testing on 12 Aspergillus fumigatus clinical
isolates (6 transplant recipients and 6 nontransplant patients) with three antifungal agents …

[HTML][HTML] In Vitro Interaction between Isavuconazole and Tacrolimus, Cyclosporin A, or Sirolimus against Aspergillus Species

P Schwarz, E Dannaoui - Journal of Fungi, 2020 - mdpi.com
The interaction of isavuconazole with immunosuppressors (tacrolimus, cyclosporin A, or
sirolimus) against 30 Aspergillus isolates belonging to the most common species …

Effects of host response and antifungal therapy on serum and BAL levels of galactomannan and (1→ 3)-β-D-glucan in experimental invasive pulmonary aspergillosis

R Petraitiene, V Petraitis, JD Bacher… - Medical …, 2015 - academic.oup.com
Abstract Galactomannan and (1→ 3)-β-D-glucan are useful biomarkers of invasive
pulmonary aspergillosis (IPA). However, the effects of immunosuppression on levels of …

Calcium homeostasis and signaling in fungi and their relevance for pathogenicity of yeasts and filamentous fungi

R Tisi, M Rigamonti, S Groppi, F Belotti - AIMS Molecular Science, 2016 - boa.unimib.it
Though fungi show peculiarities in the purposes and specific traits of calcium signaling
pathways, the general scheme and the most important players are well conserved if …

How we approach combination antifungal therapy for invasive aspergillosis and mucormycosis in transplant recipients

G Haidar, N Singh - Transplantation, 2018 - journals.lww.com
Invasive aspergillosis and mucormycosis are life-threatening infections in solid organ and
hematopoietic cell transplant recipients. Despite medical advancements in the care of these …

[HTML][HTML] Tacrolimus analogue produced by Bacillus amyloliquefaciens HSSN09 suppresses watermelon Fusarium wilt by antagonizing FON

BY Yang, JX Yang, G Wang, WP Dong, PL Xu, Y Zheng… - Biological Control, 2024 - Elsevier
Watermelon Fusarium wilt caused by Fusarium oxysporum f. sp. niveum (FON) is one of the
most devastating diseases in watermelon production. Biological control approaches are …