The cellular and molecular basis of somatosensory neuron development
Primary somatosensory neurons convey salient information about our external environment
and internal state to the CNS, allowing us to detect, perceive, and react to a wide range of …
and internal state to the CNS, allowing us to detect, perceive, and react to a wide range of …
Neurotrophin signalling: novel insights into mechanisms and pathophysiology
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …
of neuronal survival, growth and differentiation during development. While trophic factors are …
Neurotrophins and their receptors: a convergence point for many signalling pathways
MV Chao - Nature Reviews Neuroscience, 2003 - nature.com
The neurotrophins are a family of proteins that are essential for the development of the
vertebrate nervous system. Each neurotrophin can signal through two different types of cell …
vertebrate nervous system. Each neurotrophin can signal through two different types of cell …
[HTML][HTML] Brain-derived neurotrophic factor
DK Binder, HE Scharfman - Growth factors (Chur, Switzerland), 2004 - ncbi.nlm.nih.gov
Nerve growth factor (NGF) was discovered in the early 1950s due to its trophic (survival-and
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …
growth-promoting) effects on sensory and sympathetic neurons (Levi-Montalcini and …
Neurotrophic factors: an overview
SD Skaper - Neurotrophic Factors: Methods and Protocols, 2018 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …
factors for sympathetic and sensory neurons and have since been shown to control a …
Gene regulation and DNA damage in the ageing human brain
The ageing of the human brain is a cause of cognitive decline in the elderly and the major
risk factor for Alzheimer's disease. The time in life when brain ageing begins is undefined …
risk factor for Alzheimer's disease. The time in life when brain ageing begins is undefined …
Cell-signalling dynamics in time and space
BN Kholodenko - Nature reviews Molecular cell biology, 2006 - nature.com
The specificity of cellular responses to receptor stimulation is encoded by the spatial and
temporal dynamics of downstream signalling networks. Temporal dynamics are coupled to …
temporal dynamics of downstream signalling networks. Temporal dynamics are coupled to …
BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis
CR Bramham, E Messaoudi - Progress in neurobiology, 2005 - Elsevier
Interest in BDNF as an activity-dependent modulator of neuronal structure and function in
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …
the adult brain has intensified in recent years. Localization of BDNF-TrkB to glutamate …
The neurotrophin family of neurotrophic factors: an overview
SD Skaper - Neurotrophic factors: Methods and protocols, 2012 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …
factors for sympathetic and sensory neurons and have since been shown to control a …