Peroxisome proliferator-activated receptors and the hallmarks of cancer

N Wagner, KD Wagner - Cells, 2022 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …

Polarization of microglia and its therapeutic potential in sepsis

LVG Castro, CF Gonçalves-de-Albuquerque… - International Journal of …, 2022 - mdpi.com
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection, leaving the inflammation process without a proper resolution, leading to tissue …

Peroxisome proliferator‐activated receptors as therapeutic target for cancer

Y Wang, F Lei, Y Lin, Y Han, L Yang… - Journal of Cellular and …, 2024 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs) are transcription factors belonging to
the nuclear receptor family. There are three subtypes of PPARs, including PPAR‐α, PPAR …

The role of lncRNAs/miRNAs/Sirt1 axis in myocardial and cerebral injury

S Barangi, AW Hayes, G Karimi - Cell Cycle, 2023 - Taylor & Francis
In recent years, researchers have begun to realize the importance of the role of non-coding
RNAs in the treatment of cancer and cardiovascular and neurological diseases. LncRNAs …

Bioinformatics and experimental analyses of glutamate receptor and its targets genes in myocardial and cerebral ischemia

W Liao, C He, S Yang, M Zhou, C Zeng, M Luo, J Yu… - BMC genomics, 2023 - Springer
Background There is a mutual hemodynamic and pathophysiological basis between the
heart and brain. Glutamate (GLU) signaling plays an important role in the process of …

Host-microbiota interactions: The aryl hydrocarbon receptor in the acute and chronic phases of cerebral ischemia

X Fan, S Wang, S Hu, B Yang, H Zhang - Frontiers in immunology, 2022 - frontiersin.org
The relationship between gut microbiota and brain function has been studied intensively in
recent years, and gut microbiota has been linked to a couple of neurological disorders …

Aspects of xenobiotics and their receptors in stroke

A Datta, B Ghosh, D Sarmah, A Chaudhary… - …, 2023 - mednexus.org
Stroke is devastating and the second leading cause of disability and death worldwide. The
pathophysiology of stroke is intricate involving oxidative stress, ionic imbalance, and …

Role of PPAR Receptor and Ligands in the Pathogenesis and Therapy of Hematologic Malignancies

J Wu, M Zhang, A Faircloth - Hemato, 2022 - mdpi.com
The Peroxisome proliferator-activated receptors (PPARs) play vital roles in regulating
cellular differentiation, proliferation, and caspase-mediated cell death pathways. They are …

[PDF][PDF] Peroxisome Proliferator-Activated Receptors and the Hallmarks of Cancer. Cells 2022, 11, 2432

N Wagner, KD Wagner - 2022 - researchgate.net
Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …

Interaction of Vasopressin with Hormones of the Hypothalamo-Pituitary-Adrenal Axis: Significance for Therapeutic Strategies in Cardiovascular and Metabolic …

EK Szczepańska-Sadowska, K Czarzasta… - 2024 - preprints.org
A multiple number of studies provide evidence that vasopressin (AVP) and steroid hormones
are frequently secreted together and closely cooperate in the regulation of blood pressure …