The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients
up to three decades after organ transplantation implies the migration and survival of donor …

The purpose of this study was to determine the effect of dendritic cell (DC) transfers on the
incidence of diabetes in female nonobese diabetic (NOD) mice. Groups of 4-wk-old NOD …

Diabetes susceptibility in non-obese diabetic (NOD) mice may entail faulty activation of
immunoregulatory cells resulting from cytokine deficiencies. Depletion of T cells prevents …

Dendritic cells (DC) present Ag to naive T cells and are therefore pivotal in shaping immune
responses. DC may either immunize or tolerize T cells. Humans with pancreatic islet …

Five out of five allo-specific cytotoxic T lymphocyte (CTL) clones tested strongly suppressed
the development of CTLs directed against the H-2 haplotype of the CTL clone and …

Cultured, unprimed spleen cells suppress the generation of cytolytic T lymphocytes when
added to mixed lymphocyte culture of cells disparate at minor histocompatibility (H) loci …

Accessory function of monocytes for T-cell activation was studied in patients with systemic
lupus erythematosus (SLE). Nylon column-purified T cells alone were not activated to …

The murine alloantigen, Ly‐6C, is found on 45% of bone marrow cells, 25% of splenocytes
and 15% of lymph node cells in all inbred strains of mice tested, with the exception of NOD …

Abundant evidence now exists that autoimmunity plays a critical role in the pathogenesis of
type 1 (insulin-dependent) diabetes mellitus. The non-obese diabetic (NOD) mouse is an …

Suppressor T cell function in the spontaneously hypertensive rat (SHR) and normotensive
Wistar Kyoto (WKY) rats was analyzed using syngeneic mixed lymphocyte reaction (SMLR) …