Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease
TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …
processes related to their structural diversity, and based on this can be broadly classified …
Fatty acid transport and signaling: mechanisms and physiological implications
D Samovski, M Jacome-Sosa… - Annual review of …, 2023 - annualreviews.org
Long-chain fatty acids (FAs) are components of plasma membranes and an efficient fuel
source and also serve as metabolic regulators through FA signaling mediated by membrane …
source and also serve as metabolic regulators through FA signaling mediated by membrane …
[HTML][HTML] CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
JW Hao, J Wang, H Guo, YY Zhao, HH Sun… - Nature …, 2020 - nature.com
Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains
unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in …
unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in …
Endothelial cell CD36 regulates membrane ceramide formation, exosome fatty acid transfer and circulating fatty acid levels
Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs
transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of …
transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of …
Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …
The cell biology of fat expansion
Adipose tissue is a complex, multicellular organ that profoundly influences the function of
nearly all other organ systems through its diverse metabolite and adipokine secretome …
nearly all other organ systems through its diverse metabolite and adipokine secretome …
CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease
JFC Glatz, LC Heather… - Physiological reviews, 2024 - journals.physiology.org
The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …
Regulation of adipocyte lipolysis
G Frühbeck, L Méndez-Giménez… - Nutrition research …, 2014 - cambridge.org
In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease
JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …
homeostasis, particularly in the formation and dynamic properties of biological membranes …
Taste of fat: a sixth taste modality?
P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …
decade, the mechanisms responsible for this specific eating behavior have been actively …