The effects of medicinal plants and bioactive natural compounds on homocysteine

MA Atazadegan, M Bagherniya, G Askari, A Tasbandi… - Molecules, 2021 - mdpi.com
Background: Among non-communicable diseases, cardiovascular diseases (CVDs) are the
leading cause of mortality and morbidity in global communities. By 2030, CVD-related …

Chemoprotective effect of taurine on potassium bromate-induced DNA damage, DNA-protein cross-linking and oxidative stress in rat intestine

MK Ahmad, AA Khan, SN Ali, R Mahmood - PloS one, 2015 - journals.plos.org
Potassium bromate (KBrO3) is widely used as a food additive and is a major water
disinfection by-product. It induces multiple organ toxicity in humans and experimental …

Structural and functional characterization of simvastatin-induced myotoxicity in different skeletal muscles

NS Ozek, IB Bal, Y Sara, R Onur, F Severcan - Biochimica et Biophysica …, 2014 - Elsevier
Background Statins are the most commonly used drugs for the treatment of
hypercholesterolemia. Their most frequent side effect is myotoxicity. To date, it remains …

Study of genotoxic, antigenotoxic and antioxidant activities of the digallic acid isolated from Pistacia lentiscus fruits

W Bhouri, S Derbel, I Skandrani, J Boubaker, I Bouhlel… - Toxicology in Vitro, 2010 - Elsevier
The digallic acid obtained from the fruit Pistacia lentiscus exhibits an inhibitory activity
against nitrofurantoine and B [a] P induced genotoxicity when tested by the SOS chromotest …

Investigation of the distribution and season regularity of resveratrol in Vitis amurensis via HPLC–DAD–MS/MS

M Ji, Q Li, H Ji, H Lou - Food chemistry, 2014 - Elsevier
This study aims to investigate the change trend of resveratrol contents in different tissues of
Vitis amurensis Rupr. during the different seasons in a year. A rapid and sensitive method …

Determination of simvastatin-induced changes in bone composition and structure by Fourier transform infrared spectroscopy in rat animal model

S Garip, F Severcan - Journal of pharmaceutical and biomedical analysis, 2010 - Elsevier
Simvastatin is a hypolipidemic drug which is used to control hypercholesterolemia and to
prevent cardiovascular disease. In the current study, the effects of high and low doses of …

Effects of vanillin on potassium bromate-induced neurotoxicity in adult mice: impact on behavior, oxidative stress, genes expression, inflammation and fatty acid …

H Ben Saad, N Kharrat, D Driss… - … of physiology and …, 2017 - Taylor & Francis
Context: Vanillin is known to possess important antioxidant activity. Objective: The current
study was conducted to establish the therapeutic efficiency of vanillin against potassium …

Protective Effects of Extracts and Flavonoids Isolated from Scutia buxifolia Reissek against Chromosome Damage in Human Lymphocytes Exposed to Hydrogen …

AA Boligon, MR Sagrillo, LF Machado… - Molecules, 2012 - mdpi.com
Flavonoids are claimed to protect against cardiovascular disease, certain forms of cancer
and ageing, possibly by preventing initial DNA damage. Therefore, we investigated the …

Optimized Extraction of Resveratrol from Arachis repens Handro by Ultrasound and Microwave: A Correlation Study with the Antioxidant Properties and Phenol …

L Garcia, R Garcia, G Pacheco, F Sutili… - The Scientific World …, 2016 - Wiley Online Library
The vegetal species Arachis repens, commonly known as peanut grass, was studied and, for
the first time, we detected the presence of the bioactive compound trans-resveratrol (t‐RSV) …

Low dose simvastatin induces compositional, structural and dynamic changes in rat skeletal extensor digitorum longus muscle tissue

N Ozek Simsek, Y Sara, R Onur… - Bioscience reports, 2010 - portlandpress.com
Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are
many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain …