The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Neutrophils are immune cells that are well known to be present during many types of lung
diseases associated with acute respiratory distress syndrome (ARDS) and may contribute to …

Unlike solid organs, human airway epithelia derive their oxygen from inspired air rather than
the vasculature. Many pulmonary diseases are associated with intraluminal airway …

The interaction between respiratory pathogens and their hosts is complex and incompletely
understood. This is particularly true when pathogens encounter the mucus layer covering …

Human respiratory syncytial virus (RSV) is the most important cause of severe lower
respiratory tract disease (LRTD) in young children worldwide. Extensive neutrophil …

Wastewater-based surveillance can be a valuable tool to monitor viral circulation and serve
as an early warning system. For respiratory viruses that share similar clinical symptoms …

Respiratory syncytial virus (RSV) is a globally prevalent cause of lower respiratory infection
in neonates and infants. Despite its disease burden, a safe and effective RSV vaccine has …

Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract
disease, especially in young children. Despite its global impact on healthcare, related to its …

COVID-19 is an acute respiratory infection accompanied by pneumonia caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has affected millions of …

Enterovirus A71 causes severe disease upon systemic infection, sometimes leading to life-
threatening neurological dysfunction. However, in most cases infection is asymptomatic and …