Understanding cellular behavior in a quantitative manner will provide valuable information
to reveal the mechanism of diseases and immune defense and for the discovery of new …

Purpose The experimental objective of this research was to develop and validate a
mechanical device that can generate lifelike fluidic pharmacokinetic (PK) profiles for any …

Silver-based systems activated by low intensity direct current continue to be investigated as
an alternative antimicrobial for infection prophylaxis and treatment. However there has been …

New chemotherapeutic agents are urgently needed to control the spread of multidrug-
resistant (MDR) and extensively drug-resistant (XDR) forms of tuberculosis, which still …

India has the task of eliminating tuberculosis (TB) by 2025. This translates to curing about
two million TB cases present today as well as reducing the TB infection rates rapidly (WHO …

The past decades have witnessed an rise in the number of multidrug resistant bacteria,
concurrent drug failures, and declining cure rates of several fatal bacterial infectious …

The rapid diagnosis of tuberculosis (TB) and latent tuberculosis infections (LTBI) is a
significant problem in clinical practice. The aim of this study was to evaluate the diagnostic …

This thesis focuses on combating antibacterial resistance by developing novel in vitro and in
silico techniques. In vitro techniques such as in vitro pharmacodynamic (IVPD) modeling are …

The therapeutic potential of several plant species and necessity for scientific validation of the
use of plant derived medicines has prompted interest in field of traditional medicines …

In the last 40 years, only rifapentine and bedaquiline have been approved in the USA for the
treatment of active tuberculosis. Therefore, one focus of research involves optimizing the …