Objective (s): Over the past 20 years, increasing interest in the use of medicinal plants as
alternative or adjuvant treatments of several chronic diseases was observed. Accordingly …

Abstract Ethnopharmacological relevance In Iranian traditional medicine, Cuminum
cyminum is a unique medicinal herb for pain relief. Cuminaldehyde has been distinguished …

Breast cancer (BC) is not only a mass of malignant cells but also a systemic inflammatory
disease. BC pro-tumorigenic inflammation has been shown to promote immune evasion and …

Objective (s): Neuropathic pain is a prevalent and debilitating neurological disorder. Ample
evidence indicates that microglial cells and inflammatory cytokines are involved in the …

Background and purpose The oil of Nigella sativa (NS) seeds has analgesic and anti-
inflammatory effects. Therefore, the efficacy and safety of NS oil in the treatment of knee …

Thymoquinone (TQ) is an active constituent in Nigella sativa (black cumin) and is
extensively reported for its distinguished antioxidant and anti-inflammatory bioactivities …

Abstract Cuminic alcohol (4-isopropylbenzyl alcohol; 4-IPBA) is a monocyclic terpenoid
found in the analgesic medicinal plants Cuminum cyminum and Bunium persicum. The …

Medicinal plants and their ingredients have beneficial effects on human health. Nigella
sativa is a herbal plant with multiple biological and pharmacological activities. Previous …

Pain is one of the most common medical challenges, reducing life quality. Despite the
progression in pain management, it has remained a clinical challenge, which raises the …

Ethnopharmacological relevance Rhus genus is commonly known as sumac and widely
used in the folk medicine. Rhus virens is a plant commonly used to treat diabetes or pain in …