Particulate matter (PM) is a complex, heterogeneous mixture that changes in time and
space. It encompasses many different chemical components and physical characteristics …

Inhalation of metal (loid) s in ambient particulate matter (APM) represents a significant
exposure pathway to humans. Although exposure assessment associated with this pathway …

Background: Lung macrophages, that is, the intravascular, interstitial, pleural, and surface
macrophages, are part of the mononuclear phagocyte system. They are derived from the …

We review literature providing insights on health-related effects caused by inhalation of
ambient air particulate matter (PM) containing metals, emphasizing effects associated with in …

Background Epidemiologic studies indirectly suggest that the inhalation of carbonaceous
particulate matter impairs lung function in children. Using the carbon content of airway …

With the rapid growth of the nanotechnology industry, the need to understand the biological
effects of aerosol exposure has become increasingly important. Featuring contributions by …

The role of macrophages in the clearance of particles with diameters less than 100 nm
(ultrafine or nanoparticles) is not well established, although these particles deposit highly …

Although the potential human health impacts from exposure to engineered nanoparticles
(ENPs) are uncertain, past epidemiological studies have established correlations between …

Particle-bound pollutants can pose a health risk to humans. Inhalation exposure evaluated
by total contaminant concentrations significantly overestimates the potential risk. To assess …

Introduction 3. Biological pathways of PM-induced ROS generation 4. PM perturbation of
mitochondrial function 4.1. Mechanism 1: Effects on the mitochondrial electron transfer chain …