Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections

Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …

Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Resistance of gram-positive bacteria to current antibacterial agents and overcoming approaches

B Jubeh, Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
The discovery of antibiotics has created a turning point in medical interventions to
pathogenic infections, but unfortunately, each discovery was consistently followed by the …

Antibiotic resistance in Staphylococcus aureus. Current status and future prospects

TJ Foster - FEMS microbiology reviews, 2017 - academic.oup.com
The major targets for antibiotics in staphylococci are (i) the cell envelope,(ii) the ribosome
and (iii) nucleic acids. Several novel targets emerged from recent targeted drug discovery …

Multidrug‐resistant bacteria: their mechanism of action and prophylaxis

A Bharadwaj, A Rastogi, S Pandey… - BioMed research …, 2022 - Wiley Online Library
In the present scenario, resistance to antibiotics is one of the crucial issues related to public
health. Earlier, such resistance to antibiotics was limited to nosocomial infections, but it has …

Antimicrobial Resistance in Enterococcus spp. of animal origin

C Torres, CA Alonso, L Ruiz‐Ripa… - … in bacteria from …, 2018 - Wiley Online Library
Enterococcus species are natural inhabitants of the intestinal tract in humans and animals,
and due to their ubiquity in human and animal feces and their persistence in the …

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

Mechanisms of antibiotic resistance

JM Munita, CA Arias - Virulence mechanisms of bacterial …, 2016 - Wiley Online Library
The discovery, commercialization, and routine administration of antimicrobial compounds to
treat infections revolutionized modern medicine and changed the therapeutic paradigm …

Outpatient antibiotic use in Europe and association with resistance: a cross-national database study

H Goossens, M Ferech, R Vander Stichele, M Elseviers - The Lancet, 2005 - thelancet.com
Background Resistance to antibiotics is a major public-health problem and antibiotic use is
being increasingly recognised as the main selective pressure driving this resistance. Our …

Antimicrobial resistance: the example of Staphylococcus aureus

FD Lowy - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
S. aureus infections in intensive care units in the National Nosocomial Infections
Surveillance System. Data include the total number of infections from 1987 to 1997. Isolates …