B and T lymphocyte attenuator (BTLA) is one of the most important cosignaling molecules. It
belongs to the CD28 superfamily and is similar to programmed cell death-1 (PD-1) and …

In recent years, immunotherapy has been revolutionized by a new approach that works by
blocking receptors called immune checkpoints (IC). These molecules play a key role in …

Immune checkpoints play a critical role in maintaining the delicate balance of immune
activation in order to prevent potential harm caused by excessive activation, autoimmunity …

Opinion statement Increasing understanding of the complex interaction between leukemic
and immune cells, which is responsible for tumor progression and immune evasion, has …

Introduction Lung cancer is the predominant cause of death among cancer patients and non-
small cell lung cancer (NSCLC) is the most common type. Cigarette smoking is the …

Chronic lymphocytic leukemia (CLL) is characterized by the peripheral accumulation of
neoplastic B cells and is frequently complicated by the systemic immunosuppression …

Somatic mutations in cancer cells may influence tumor growth, survival, or immune
interactions in their microenvironment. The tumor necrosis factor receptor family member …

One of the causes of inborn errors of immunity is immune dysregulation. The inability of the
immune system to regulate the extent of its activity has several deleterious effects, including …

Background The important roles of B7 homologous body 4 (B7-H4), B and T lymphocyte
attenuator (BTLA) in patients with pulmonary tuberculosis (PTB) have been reported. This …

Immunotherapy has emerged as a revolutionary cancer treatment, particularly with the
introduction of immune checkpoint inhibitors (ICIs). ICIs target specific proteins that restrain …