Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …

Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …

This research work focuses on the synthesis, spectroscopic characterization, DFT studies,
and in silico molecular docking of two azo compounds;(E)-6-((4, 6-dichloro-1, 3, 5-triazin-2 …

High-grade gliomas (World Health Organization grades III and IV) are the most frequent and
fatal brain tumors, with median overall survivals of 24–72 and 14–16 months, respectively …

Among children and adolescents in the United States (0 to 19 years old), brain and other
central nervous system tumors are the second most common types of cancers, surpassed in …

Ferroptosis is an iron‐dependent cell death process mainly triggered by reactive oxygen
species (ROS) and lipid peroxidation. Thioredoxin domain protein 12 (TXNDC12) promotes …

The central nervous system represents a complex environment in which glioblastoma
adapts skillfully, unleashing a series of mechanisms suitable for its efficient development …

Simple Summary Preclinical models are essential for the advancement of our understanding
of glioma biology and the development of novel therapeutics. Much of our progress in the …

Notorious for its high mortality rate, the current standard treatment for high-grade gliomas
remains a challenge. This is largely due to the complex heterogeneity of the tumour coupled …

Diffuse midline glioma (DMG) is a pediatric cancer that originates in the midline structures of
the brain. Prognosis of DMG patients remains poor due to the infiltrative nature of these …