Introduction Prurigo nodularis (PN) is a chronic inflammatory skin condition that presents
with intensely pruritic, hyperkeratotic nodules. The pathophysiology underlying PN is not …

Prurigo nodularis (PN) is an inflammatory skin condition characterized by intensely pruritic
nodules on the skin. Patients with PN suffer from an intractable itch–scratch cycle leading to …

Hepatology AASLD Publications Hepatology Liver Transplantation Clinical Liver Disease
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Prurigo nodularis (PN) is an intensely pruritic, inflammatory skin disease with a poorly
understood pathogenesis. We performed single-cell transcriptomic profiling of 28,695 …

Chronic prurigo is a debilitating, difficult-to-treat, and long-neglected disease characterized
by chronic pruritus, signs of repeated scratching, and the presence of pruriginous lesions …

Background Prurigo nodularis, a chronic inflammatory skin condition, adversely affects the
quality of life of affected individuals. Current treatment options for prurigo nodularis in Japan …

Pruritus of lymphoma is commonly associated with both Hodgkin lymphoma (HL) and
angioimmunoblastic T cell lymphoma (AITL) and critically affects the life quality of patient …

The interleukins IL-4 and IL-13 are increasingly recognized contributors to the pathogenesis
of cutaneous T cell lymphomas (CTCLs), and their role in disease-associated pruritus is …

Importance Chronic pruritus, defined as itch experienced for 6 weeks or longer, affects
approximately 22% of people in their lifetime. Approximately 1% of physician visits are for …

Importance Prurigo nodularis (PN) and chronic pruritus of unknown origin (CPUO) are
chronic pruritic diseases that dramatically impair quality of life, but therapeutic options are …