A review of CDKL: An underestimated protein kinase family
C Li, Y Liu, S Luo, M Yang, L Li, L Sun - International Journal of Biological …, 2024 - Elsevier
Cyclin-dependent kinase-like (CDKL) family proteins are serine/threonine protein kinases
and is a specific branch of CMGC (including CDK, MAPK, GSK). Its name is due to the …
and is a specific branch of CMGC (including CDK, MAPK, GSK). Its name is due to the …
Mutations in ARHGEF15 cause autosomal dominant hereditary cerebral small vessel disease and osteoporotic fracture
X Ding, Y Chen, C Guo, Y Fu, C Qin, Q Zhu… - Acta …, 2023 - Springer
Cerebral small vessel disease (CSVD) is a prominent cause of ischemic and hemorrhagic
stroke and a leading cause of vascular dementia, affecting small penetrating vessels of the …
stroke and a leading cause of vascular dementia, affecting small penetrating vessels of the …
MYCT1 controls environmental sensing in human haematopoietic stem cells
The processes that govern human haematopoietic stem cell (HSC) self-renewal and
engraftment are poorly understood and challenging to recapitulate in culture to reliably …
engraftment are poorly understood and challenging to recapitulate in culture to reliably …
FLI1 is associated with regulation of DNA methylation and megakaryocytic differentiation in FPDMM caused by a RUNX1 transactivation domain mutation
Y Tanaka, Y Nakanishi, E Furuhata, K Nakada… - Scientific Reports, 2024 - nature.com
Familial platelet disorder with associated myeloid malignancies (FPDMM) is an autosomal
dominant disease caused by heterozygous germline mutations in RUNX1. It is characterized …
dominant disease caused by heterozygous germline mutations in RUNX1. It is characterized …
DNA methylation analysis using RUNX1-mutated cells reveals association of FLI1 to familial platelet disorder with associated myeloid malignancies caused by a …
Y Tanaka, K Nakada, R Maruyama, H Suzuki, T Suzuki - 2024 - researchsquare.com
Background Familial platelet disorder with associated myeloid malignancies (FPDMM) is an
autosomal dominant disease caused by heterozygous germline mutations in RUNX1. It is …
autosomal dominant disease caused by heterozygous germline mutations in RUNX1. It is …