Background and Purpose The NLR family pyrin domain‐containing 3 (NLRP3)
inflammasome is activated in many inflammatory conditions. So far, no low MW compounds …

Postoperative delirium (POD) is an acute cognitive dysfunction that is mainly characterized
by memory impairment and disturbances in consciousness. POD can prolong the hospital …

Activation of NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome
plays a crucial role in the inflammatory responses of monosodium urate (MSU) crystal …

Doxorubicin (DOX) is used extensively in anticancer therapy, but its clinical application is
limited due to its cardiotoxicity. Carnosic acid (CA) is a bioactive compound found in …

The NLRP3 inflammasome is a crucial constituent of the body's innate immune system, and
a multiprotein platform which is initiated by pattern recognition receptors (PRRs). Its …

Atherosclerosis (AS) is chronic pathological process based on the inflammatory reaction
associated with factors including vascular endothelial dysfunction, inflammation, and …

Autophagy degrades phagocytosed damaged organelles, misfolded proteins, and various
pathogens through lysosomes as an essential way to maintain cellular homeostasis …

Pyroptosis is a form of cell death that is characterized by the destruction of the cell, and it has
implications in both the immune system and cancer immunotherapy. The gasdermin family is …

The role of the NLRP3 inflammasome is pivotal in the pathophysiology and progression of
diabetes mellitus (DM), encompassing both type 1 (T1D), or type 2 (T2D). As part of the …

Influenza virus infection is one of the strongest pathogenic factors for the development of
acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). However, the underlying …