The inflammasome is an immune multiprotein complex that activates pro-caspase 1 in
response to inflammation-inducing stimuli and it leads to IL-1β and IL-18 proinflammatory …

Abstract Ethnopharmacological relevance Shiwei Qingwen decoction (SWQ), a Chinese
herbal formula based on the classic traditional Chinese medicine prescription Yu Ping Feng …

Aluminum (Al) is a common environmental pollutant that can induce kidney damage.
However, the mechanism is not clear. In the present study, to explored the exact mechanism …

The changes of inflammation and metabolism are two features in nonalcoholic
steatohepatitis (NASH). However, how they interact to regulate NASH progression remains …

Neuroinflammation plays a vital role in cerebral ischemic stroke (IS). In the acute phase of
IS, microglia are activated toward the pro-inflammatory (M1) and anti-inflammatory (M2) …

In recent years, a new target closely linked to a variety of diseases has appeared in the
researchers' vision, which is the NLRP3 inflammasome. With the deepening of the study of …

Renal transplantation is currently the best treatment option for patients with end-stage
kidney disease. Ischemia/reperfusion injury (IRI), which is an inevitable event during renal …

Lupus nephritis (LN) is a type of immune-complex nephritis caused by systemic lupus
erythematosus and is a major contributor to mortality and morbidity. Honokiol (HNK) has …

Pyroptosis has an important role in liver inflammation and fibrosis. The role of KC pyroptosis
in liver fibrosis was unclear. Ursolic acid (UA) has antifibrotic effects, but study on the effect …

Inflammasomes are cytoplasmic multiprotein complexes formed by the host's immune
system as a response to microbial infection and cellular damage. Many studies have …