Background Honokiol (HKL) has been reported to ameliorate lipopolysaccharide (LPS)-
induced acute lung injury (ALI). However, its potential mechanism of its protective effects …

The endogenous metabolite itaconate and its cell‑permeable derivative dimethyl itaconate
(DI) have been identified as anti‑inflammatory regulators of macrophages; however, their …

It has been previously reported that macrophages may be involved in diabetic nephropathy
(DN) development. Furthermore, Bruton's tyrosine kinase (BTK) may participate in …

The aseptic inflammatory response of the central nervous system is one of the important
causes of neurodegenerative diseases in individuals and is also recognized in …

Pyroptosis is a type of programmed cell death that is generally upregulated during
atherosclerosis (AS). Magnesium, an important cation in the body, has exhibited an …

Inflammasomes are important modulators of inflammation. Dysregulation of inflammasomes
can enhance vulnerability to conditions such as neurodegenerative diseases …

Several studies have demonstrated that neuroinflammation is the key to perioperative
neurocognitive disorders (PND); however, the specific mechanism postsurgery and …

Radiation-induced enteropathy (RIE) is one of the most common and fatal complications of
abdominal radiotherapy, with no effective interventions available. Pyroptosis, a form of …

Magnolol, a natural extract from magnolia officinalis, has received growing interest in its
bioactive properties such as antioxidant, anti-inflammatory, and antibacterial activities …

N6-methyladenosine (m6A) plays a role in various diseases, but it has rarely been reported
in acute lung injury (ALI). The FTO (fat mass and obesity-associated) protein can regulate …