Emerging roles of macrophage polarization in osteoarthritis: Mechanisms and therapeutic strategies
Z Yuan, D Jiang, M Yang, J Tao, X Hu… - Orthopaedic …, 2024 - Wiley Online Library
Osteoarthritis (OA) is the most common chronic degenerative joint disease in middle‐aged
and elderly people, characterized by joint pain and dysfunction. Macrophages are key …
and elderly people, characterized by joint pain and dysfunction. Macrophages are key …
[HTML][HTML] Mitochondria of intestinal epithelial cells in depression: Are they at a crossroads of gut-brain communication?
Y Wang, H Lai, T Zhang, J Wu, H Tang, X Liang… - Neuroscience & …, 2023 - Elsevier
The role of gut dysbiosis in depression is well established. However, recent studies have
shown that gut microbiota is regulated by intestinal epithelial cell (IEC) mitochondria, which …
shown that gut microbiota is regulated by intestinal epithelial cell (IEC) mitochondria, which …
Advances in understanding the innate immune‐associated diabetic kidney disease
S Wan, S Wan, X Jiao, H Cao, Y Gu, L Yan… - The FASEB …, 2021 - Wiley Online Library
Millions of human deaths occur annually due to chronic kidney disease, caused by diabetic
kidney disease (DKD). Despite having effective drugs controlling the hyperglycemia and …
kidney disease (DKD). Despite having effective drugs controlling the hyperglycemia and …
Anemoside B4 ameliorates dextran sulfate sodium (DSS)-induced colitis through inhibiting NLRP3 inflammasome and modulating gut microbiota
W Feng, Y Zhang, Y Zhang, Y Dong, J Wu… - European Journal of …, 2024 - Elsevier
Ulcerative colitis (UC) has been recognized as a chronic and relapsing inflammatory
disease of the gastrointestinal tract. Clinically, aminosalicylates, immunosuppressants and …
disease of the gastrointestinal tract. Clinically, aminosalicylates, immunosuppressants and …
Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infection
J Liu, QX Chen, WF Wu, D Wang, SY Zhao, JH Li… - European Journal of …, 2024 - Elsevier
The increasing antibiotic resistance driven by Pseudomonas aeruginosa typically leads to
uncontrolled and persistent inflammatory damage, which is primarily attributed to the …
uncontrolled and persistent inflammatory damage, which is primarily attributed to the …
Inflammasomes in human reproductive diseases
Y Chen, C Miao, Y Zhao, L Yang… - Molecular Human …, 2023 - academic.oup.com
Inflammasomes are multi-protein complexes localized within immune and non-immune cells
that induce caspase activation, proinflammatory cytokine secretion, and ultimately pyroptosis …
that induce caspase activation, proinflammatory cytokine secretion, and ultimately pyroptosis …
[HTML][HTML] Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by …
Q Shan, N Liu, X Wang, Y Zhu, J Yin… - Journal of Animal Science …, 2022 - Springer
Background Bacillus cereus is an important pathogen that causes human food poisoning,
specifically diarrhea and vomiting. B. cereus can also induce mastitis in dairy cows and has …
specifically diarrhea and vomiting. B. cereus can also induce mastitis in dairy cows and has …
[HTML][HTML] Resveratrol ameliorates glioblastoma inflammatory response by reducing NLRP3 inflammasome activation through inhibition of the JAK2/STAT3 pathway
C Zhang, Q Peng, Y Tang, C Wang, S Wang… - Journal of Cancer …, 2024 - Springer
Objectives The aim of this study was to investigate the anti-tumor effect of resveratrol (RSV)
on glioblastoma (GBM) and its specific mechanism in improving the inflammatory response …
on glioblastoma (GBM) and its specific mechanism in improving the inflammatory response …
Component identification of modified sanmiao pills by UPLC-Xevo G2-XS QTOF and its anti-gouty arthritis mechanism based on network pharmacology and …
R Chen, F Li, K Zhou, M Xing, X Zhang, X Zhao… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Modified sanmiao pills (MSMP), a traditional Chinese
medicine (TCM) formula, is consisted of rhizome of Smilax glabra Roxb., Cortexes of …
medicine (TCM) formula, is consisted of rhizome of Smilax glabra Roxb., Cortexes of …
(−)‐Epigallocatechin gallate alleviates chronic unpredictable mild stress‐induced depressive symptoms in mice by regulating the mTOR autophagy pathway and …
Y Zhang, H Wu, C Xu, S Li, Y Hu, Z Zhang… - Food Science & …, 2024 - Wiley Online Library
Depression is a global public health issue that is widely studied due to the large number of
people it affects and its serious consequences. Clinical studies have shown that regular tea …
people it affects and its serious consequences. Clinical studies have shown that regular tea …