Exercise mimetics: harnessing the therapeutic effects of physical activity

C Gubert, AJ Hannan - Nature Reviews Drug Discovery, 2021 - nature.com
Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …

Beneficial intergenerational effects of exercise on brain and cognition: a multilevel meta‐analysis of mean and variance

Y Yang, M Lagisz, YZ Foo, DWA Noble… - Biological …, 2021 - Wiley Online Library
Physical exercise not only helps to improve physical health but can also enhance brain
development and cognition. Recent reports on parental (both maternal and paternal) effects …

Maternal high-intensity interval training as a suitable approach for offspring's heart protection in rat: evidence from oxidative stress and mitochondrial genes

R Mohammadkhani, A Komaki, SA Karimi… - Frontiers in …, 2023 - frontiersin.org
Considerable scientific evidence suggests that the intrauterine environment plays a crucial
role in determining the long-term health of offspring. The present study aims to investigate …

Resistance exercise was safe for the pregnancy and offspring's development and partially protected rats against early life stress-induced effects

AS Dos Santos, E Segabinazi, W de Almeida… - Behavioural Brain …, 2023 - Elsevier
Promising evidence points to gestational physical exercise as the key to preventing various
disorders that affect the offspring neurodevelopment, but there are no studies showing the …

Direct and inherited epigenetic changes in the nervous system caused by intensive locomotion: possible adaptive significance

MI Mezheritskiy, VE Dyakonova - Russian Journal of Developmental …, 2022 - Springer
This review is devoted to the analysis of works that investigated the long-term effects of
species-specific forms of intensive locomotion on the cognitive functions of animals and …

Epigenetic impact of the parents' physical activity on the health of their children

A Boron - Baltic Journal of Health and Physical Activity, 2021 - balticsportscience.com
All parents' dream is to have healthy children. The question whether the parents' lifestyle
affects the quality of their progeny's health has been bothering scientists and society for …

Maternal resistance exercise promotes changes in neuroplastic and epigenetic marks of offspring's hippocampus during adult life

ALF Meireles, E Segabinazi, C Spindler… - Physiology & …, 2021 - Elsevier
Studies indicate that gestational exercise practice positively impacts the offspring's
cognition. Nevertheless, the influence of maternal resistance exercise, different periods of …

Environmental Influence on Epigenetics

M Resendiz, DS Watkins, NC Öztürk, FC Zhou - Handbook of Epigenetics, 2023 - Elsevier
The epigenetic profile of an individual is built in part through an intrinsic program including
an inherited template and acquired environmental inputs throughout the lifespan. The latter …

Can Maternal Exercise Prevent High-Altitude Pulmonary Hypertension in Children?

E Leslie, AL Gibson, LV Gonzalez Bosc… - … Altitude Medicine & …, 2023 - liebertpub.com
Leslie, Eric, Ann L. Gibson, Laura V. Gonzalez Bosc, Christine Mermier, Sean M. Wilson,
and Michael R. Deyhle. Review: can maternal exercise prevent high-altitude pulmonary …

[HTML][HTML] Strength training during pregnancy influences hippocampal plasticity but not body development in neonatal rats

ALF Meireles, E Segabinazi, C Spindler… - … of Musculoskeletal & …, 2021 - ncbi.nlm.nih.gov
Objective: To describe the effects of strength exercise practice during pregnancy on the
offspring's development parameters: growth and motor performance, hippocampal …