Persistent metabolic toxicities following developmental exposure to hexafluoropropylene oxide trimer acid (HFPO-TA): Roles of peroxisome proliferator activated …

S Zhong, J Yuan, Y Niu, S Wang, X Gong, J Ji… - Journal of Hazardous …, 2024 - Elsevier
Background Hexafluoropropylene oxide trimer acid (HFPO-TA), a perfluorooctanoic acid
(PFOA) substitute, exhibited strong affinity and capability to activate peroxisome proliferator …

Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation

LC Smith, H Abramova, K Vayas… - Toxicological …, 2024 - academic.oup.com
Macrophages play a key role in ozone-induced lung injury by regulating both the initiation
and resolution of inflammation. These distinct activities are mediated by pro-inflammatory …